INT136818

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Context Info
Confidence 0.46
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.81
Pain Relevance 2.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VEGFA) growth (VEGFA) extracellular region (VEGFA)
proteinaceous extracellular matrix (VEGFA) cytoplasm (VEGFA)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 9 97.20 Very High Very High Very High
Morphine 9 85.88 High High
opiate 3 75.00 Quite High
agonist 3 68.24 Quite High
antagonist 3 67.76 Quite High
mu opioid receptor 3 67.32 Quite High
corticosteroid 7 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 2 91.36 High High
Diabetic Macular Edema 21 84.80 Quite High
Diabetes Mellitus 55 77.28 Quite High
Cancer 3 59.52 Quite High
Age-related Macular Degeneration 7 5.00 Very Low Very Low Very Low
Cataract 3 5.00 Very Low Very Low Very Low
Blindness 3 5.00 Very Low Very Low Very Low
Immunotherapy Of Cancer 3 5.00 Very Low Very Low Very Low
Retinal Diseases 2 5.00 Very Low Very Low Very Low
Fibromyalgia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MNTX inhibited MS, DAMGO and VEGF induced tyrosine phosphorylation (transactivation) of VEGF receptors 1 and 2.
Positive_regulation (induced) of Phosphorylation (phosphorylation) of VEGF
1) Confidence 0.46 Published 2006 Journal Microvasc. Res. Section Abstract Doc Link 16820176 Disease Relevance 0.06 Pain Relevance 0.67
MNTX inhibited MS, DAMGO and VEGF induced tyrosine phosphorylation (transactivation) of VEGF receptors 1 and 2.
Positive_regulation (induced) of Phosphorylation (phosphorylation) of VEGF
2) Confidence 0.43 Published 2006 Journal Microvasc. Res. Section Abstract Doc Link 16820176 Disease Relevance 0.06 Pain Relevance 0.67
MNTX inhibited MS, DAMGO and VEGF induced tyrosine phosphorylation (transactivation) of VEGF receptors 1 and 2.
Positive_regulation (transactivation) of Phosphorylation (phosphorylation) of VEGF
3) Confidence 0.43 Published 2006 Journal Microvasc. Res. Section Abstract Doc Link 16820176 Disease Relevance 0.06 Pain Relevance 0.67
Ojima et al. (25) demonstrated that VEGF-induced FLK-1 phosphorylation and its downstream signaling cascade correlated with BRB breakdown and was inhibited by EphA2/ephrinA1 both in vitro and in vivo.
Positive_regulation (induced) of Phosphorylation (phosphorylation) of VEGF
4) Confidence 0.09 Published 2008 Journal Diabetes Section Body Doc Link PMC2836241 Disease Relevance 0.64 Pain Relevance 0

General Comments

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