INT137550

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.72
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (Pygm) carbohydrate metabolic process (Pygm) cytoplasm (Pygm)
Pygm (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 29 96.96 Very High Very High Very High
Pain 12 84.96 Quite High
Arthritis 1 60.88 Quite High
Inflammation 6 28.16 Quite Low
COX2 4 25.00 Low Low
visual analogue scale 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Phosphate Metabolism Disorders 55 99.00 Very High Very High Very High
Reprotox - General 1 12 98.00 Very High Very High Very High
Pain 12 84.96 Quite High
INFLAMMATION 10 80.72 Quite High
Arthritis 1 60.88 Quite High
Fatigue 5 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 2 5.00 Very Low Very Low Very Low
Disorders Of Creatine Metabolism 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Muscle Weakness 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Calcitriol also inhibits the expression of the PG receptors EP2 and FP.
Negative_regulation (inhibits) of Gene_expression (expression) of PG
1) Confidence 0.03 Published 2006 Journal Anticancer Res. Section Abstract Doc Link 16886660 Disease Relevance 0.42 Pain Relevance 0.14
Calcitriol significantly decreases the expression of the PG synthesizing cyclooxygenase-2 (COX-2) gene, while increasing that of PG inactivating 15-prostaglandin dehydrogenase (15-PGDH).
Negative_regulation (decreases) of Gene_expression (expression) of PG
2) Confidence 0.02 Published 2006 Journal Anticancer Res. Section Abstract Doc Link 16886660 Disease Relevance 0.43 Pain Relevance 0.11
In order to avoid blocking PG synthesis for a long period of time, we now have investigated the effect of repeated NSAID treatments, each lasting 8 weeks, with an interval of four weeks in between.
Negative_regulation (blocking) of Gene_expression (synthesis) of PG associated with cinod
3) Confidence 0.01 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1533806 Disease Relevance 0.87 Pain Relevance 0.45

General Comments

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