INT138072

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Context Info
Confidence 0.42
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.02
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chn1) plasma membrane (Oprl1) signal transducer activity (Oprl1)
Anatomy Link Frequency
nervous system 1
Chn1 (Rattus norvegicus)
Oprl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
orphanin 10 100.00 Very High Very High Very High
opioid receptor 1 100.00 Very High Very High Very High
Pain 6 94.52 High High
dorsal root ganglion 5 83.92 Quite High
Inflammation 5 77.52 Quite High
IPN 3 75.00 Quite High
Root ganglion neuron 1 75.00 Quite High
Neuropathic pain 1 64.80 Quite High
Sciatic nerve 1 61.68 Quite High
Disease Link Frequency Relevance Heat
Pain 3 94.52 High High
Ganglion Cysts 6 82.96 Quite High
Nervous System Injury 3 78.88 Quite High
INFLAMMATION 2 77.52 Quite High
Inflammatory Pain 3 75.00 Quite High
Neuropathic Pain 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nociceptin (NC), by activating its receptor, the opioid receptor-like 1 (ORL1) receptor, exerts an effect on a number of functions in the nervous system including locomotion, learning and memory, and processing of pain signals.
NC Positive_regulation (activating) of ORL1 in nervous system associated with pain, orphanin and opioid receptor
1) Confidence 0.42 Published 2006 Journal J. Peripher. Nerv. Syst. Section Abstract Doc Link 16930285 Disease Relevance 1.02 Pain Relevance 0.95

General Comments

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