INT139192

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (RFFL, Fas) signal transduction (Fas) extracellular region (Fas)
plasma membrane (Fas) nucleus (Fas) cytoplasmic membrane-bounded vesicle (RFFL)
Anatomy Link Frequency
cerebral cortex 1
RFFL (Homo sapiens)
Fas (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 2 97.84 Very High Very High Very High
Opioid 3 76.12 Quite High
opioid receptor 2 75.76 Quite High
Endogenous opioid 2 70.36 Quite High
addiction 1 62.52 Quite High
opiate 3 62.12 Quite High
agonist 1 42.40 Quite Low
Disease Link Frequency Relevance Heat
Death 3 99.24 Very High Very High Very High
Opiate Addiction 1 62.52 Quite High
Apoptosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Notably, the basal content of FADD (the adaptor protein that couples Fas to caspases and transmits the death signal) was increased in the cerebral cortex of delta-KO mice (48%), but not in mu- or kappa-KO mice.
caspases Positive_regulation (couples) of Fas in cerebral cortex associated with cerebral cortex and death
1) Confidence 0.00 Published 2007 Journal Eur Neuropsychopharmacol Section Abstract Doc Link 17030115 Disease Relevance 0.30 Pain Relevance 0.61

General Comments

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