INT13929

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Context Info
Confidence 1.00
First Reported 1991
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Th) mitochondrion (Th) nucleus (Th)
response to stress (Th) cytoplasm (Th)
Anatomy Link Frequency
dorsal root ganglia 2
Th (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Catecholamine 6 100.00 Very High Very High Very High
Dopamine 2 100.00 Very High Very High Very High
Neuropeptide 2 76.00 Quite High
Enkephalin 3 75.00 Quite High
qutenza 2 59.60 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These differential effects suggest suppression of endogenous TH gene transcription, targeted degradation of TH mRNA or both.
Protein_catabolism (degradation) of TH mRNA
1) Confidence 1.00 Published 2007 Journal Brain Res. Section Abstract Doc Link 17174279 Disease Relevance 0 Pain Relevance 0.19
The presence of enzymes (tyrosine hydroxylase (TH) and dopamine-beta-hydroxylase (D beta H)) and enzymatic activities (monoamino oxidase, (MAO)) related to catecholamine synthesis and degradation have been investigated in cervical, thoracic and lumbar dorsal root ganglia (DRG) of adult male rats using immunohistochemical and enzyme histochemical techniques, respectively.
Protein_catabolism (degradation) of tyrosine hydroxylase in dorsal root ganglia associated with dopamine and catecholamine
2) Confidence 0.82 Published 1991 Journal Cell. Mol. Biol. Section Abstract Doc Link 1682049 Disease Relevance 0 Pain Relevance 0.20
The presence of enzymes (tyrosine hydroxylase (TH) and dopamine-beta-hydroxylase (D beta H)) and enzymatic activities (monoamino oxidase, (MAO)) related to catecholamine synthesis and degradation have been investigated in cervical, thoracic and lumbar dorsal root ganglia (DRG) of adult male rats using immunohistochemical and enzyme histochemical techniques, respectively.
Protein_catabolism (degradation) of TH in dorsal root ganglia associated with dopamine and catecholamine
3) Confidence 0.82 Published 1991 Journal Cell. Mol. Biol. Section Abstract Doc Link 1682049 Disease Relevance 0 Pain Relevance 0.20

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