INT139641

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Jun) extracellular region (Vip) aging (Jun)
nucleus (Jun) DNA binding (Jun) transcription factor binding (Jun)
Anatomy Link Frequency
dorsal root ganglia 3
Jun (Rattus norvegicus)
Vip (Rattus norvegicus)
Pain Link Frequency Relevance Heat
neuralgia 1 100.00 Very High Very High Very High
Neuropathic pain 3 98.40 Very High Very High Very High
Neuropeptide 1 96.08 Very High Very High Very High
Peripheral nerve injury 1 90.28 High High
Stimulus evoked pain 1 82.44 Quite High
Pain 1 79.76 Quite High
Eae 5 77.40 Quite High
Sciatic nerve 1 75.76 Quite High
intrathecal 1 75.16 Quite High
allodynia 1 70.88 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 5 98.40 Very High Very High Very High
Nervous System Injury 1 89.84 High High
Hypersensitivity 1 82.24 Quite High
Pain 1 79.76 Quite High
Injury 5 76.56 Quite High
Hyperalgesia 1 70.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of transcription factor c-jun in dorsal root ganglia induces VIP and NPY upregulation and contributes to the pathogenesis of neuropathic pain.
Positive_regulation (Activation) of c-jun in dorsal root ganglia Positive_regulation (induces) of Positive_regulation (upregulation) of VIP in dorsal root ganglia associated with neuralgia and neuropathic pain
1) Confidence 0.37 Published 2007 Journal Exp. Neurol. Section Title Doc Link 17081520 Disease Relevance 0.95 Pain Relevance 0.99

General Comments

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