INT140096

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Gtf3a) DNA binding (Gtf3a) cell-cell signaling (Edn1)
cytoplasm (Edn1) extracellular space (Edn1) extracellular region (Edn1)
Anatomy Link Frequency
connective tissue 2
Gtf3a (Rattus norvegicus)
Edn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 1 91.60 High High
Chronic pancreatitis 1 88.40 High High
fibrosis 1 86.48 High High
Disease Link Frequency Relevance Heat
Primary Sclerosing Cholangitis 2 100.00 Very High Very High Very High
Pancreatic Cancer 1 89.28 High High
Pancreatitis 1 88.40 High High
Fibrosis 1 86.48 High High
Apoptosis 1 77.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data indicate that IFN-gamma regulates the expression of two autocrine mediators of PSC activation, connective tissue growth factor and endothelin-1, in a transforming growth factor-beta1-antagonistic manner.
factor Positive_regulation (mediators) of Gene_expression (expression) of endothelin-1 in connective tissue associated with primary sclerosing cholangitis
1) Confidence 0.02 Published 2007 Journal Cell. Signal. Section Abstract Doc Link 17116388 Disease Relevance 0.44 Pain Relevance 0.18

General Comments

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