INT140191

From wiki-pain
(Difference between revisions)
Jump to: navigation, search
(Generated page)
 
(Generated page)
 
Line 10: Line 10:
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
Line 47: Line 47:
 
style=filled,
 
style=filled,
 
fillcolor=yellow,
 
fillcolor=yellow,
URL=Positive_regulation
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=E:Positive_regulation"
 
];
 
];
 
node2
 
node2
Line 54: Line 54:
 
fillcolor=green,
 
fillcolor=green,
 
label="Gene\nexpression",
 
label="Gene\nexpression",
URL=Gene_expression
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=E:Gene_expression"
 
];
 
];
 
node3
 
node3
Line 62: Line 62:
 
fontcolor=white,
 
fontcolor=white,
 
label="Mmp13",
 
label="Mmp13",
URL="Mmp13"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:17386"
 
];
 
];
 
subgraph cluster_0 {
 
subgraph cluster_0 {
Line 82: Line 82:
 
{| cellspacing=5 cellpadding=2
 
{| cellspacing=5 cellpadding=2
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[peptidase activity]] ([[Mmp13]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:peptidase activity|peptidase activity]] ([[G:17386|Mmp13]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[extracellular space]] ([[Mmp13]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:extracellular space|extracellular space]] ([[G:17386|Mmp13]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[extracellular region]] ([[Mmp13]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:extracellular region|extracellular region]] ([[G:17386|Mmp13]])
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[Golgi apparatus]] ([[Mmp13]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:Golgi apparatus|Golgi apparatus]] ([[G:17386|Mmp13]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[proteinaceous extracellular matrix]] ([[Mmp13]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:proteinaceous extracellular matrix|proteinaceous extracellular matrix]] ([[G:17386|Mmp13]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[lysosome]] ([[Mmp13]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:lysosome|lysosome]] ([[G:17386|Mmp13]])
 
|-
 
|-
 
|}
 
|}
Line 96: Line 96:
 
{| cellpadding=3 cellspacing=0  
 
{| cellpadding=3 cellspacing=0  
 
|-
 
|-
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Mention
+
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:372|cartilage]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:cartilage|cartilage]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|12
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|12
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:915|chondrocytes]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:chondrocytes|chondrocytes]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|6
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|6
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:64|joints]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:joints|joints]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|6
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|6
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:789|TMJ]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:TMJ|TMJ]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|4
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|4
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:381|MEFs]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:MEFs|MEFs]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
|-
 
|-
Line 127: Line 127:
 
{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[rheumatoid arthritis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:metalloproteinase|metalloproteinase]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 431
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 491
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[metalloproteinase]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:rheumatoid arthritis|rheumatoid arthritis]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 491
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 431
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Snapping jaw]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Osteoarthritis|Osteoarthritis]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 36
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 635
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Osteoarthritis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Snapping jaw|Snapping jaw]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 635
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[cytokine]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:cytokine|cytokine]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 137
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 137
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 94.40
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 94.40
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Arthritis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Arthritis|Arthritis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 285
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 285
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 92.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 92.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[antagonist]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:antagonist|antagonist]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 18
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 18
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 83.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 83.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Inflammation]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Inflammation|Inflammation]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 213
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 213
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 77.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 77.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Kinase C]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Kinase C|Kinase C]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 67.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 67.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[fibrosis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:fibrosis|fibrosis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 15
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 15
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 59.96
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 59.96
Line 188: Line 188:
 
{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Rheumatoid Arthritis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Rheumatoid Arthritis|Rheumatoid Arthritis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 431
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 431
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Keloid Scars]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Keloid Scars|Keloid Scars]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 50
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 50
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.90
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.90
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Temporomandibular Joint Syndrome]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Osteoarthritis|Osteoarthritis]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 36
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 671
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Osteoarthritis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Temporomandibular Joint Syndrome|Temporomandibular Joint Syndrome]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 671
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Injury]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Injury|Injury]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 38
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 38
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.30
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.30
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Burns]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Burns|Burns]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.04
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.04
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Cicatrix]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Cicatrix|Cicatrix]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 96.64
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 96.64
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Hypertrophy]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Hypertrophy|Hypertrophy]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 93.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 93.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Osteogenic Sarcomas]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Osteogenic Sarcomas|Osteogenic Sarcomas]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 93.44
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 93.44
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Arthritis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Arthritis|Arthritis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 305
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 305
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 92.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 92.00
Line 269: Line 269:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">increased</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''Mmp-13'''</span> in <span style="color:#808000">TMJ</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">increased</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''Mmp-13'''</span>]] in [[A:TMJ|<span style="color:#808000">TMJ</span>]]
 
|-
 
|-
 
|}
 
|}
Line 280: Line 280:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.67
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.67
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2009
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2009|2009]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Osteoarthr. Cartil.|Osteoarthr. Cartil.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Osteoarthr. Cartil.|Osteoarthr. Cartil.]]
Line 301: Line 301:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">overexpression</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">overexpression</span>) of <span style="color:#800000">'''Mmp-13'''</span> in <span style="color:#808000">joints</span> associated with <span style="color:#FF0000">'''osteoarthritis'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">overexpression</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">overexpression</span>) of [[G:17386|<span style="color:#800000">'''Mmp-13'''</span>]] in [[A:joints|<span style="color:#808000">joints</span>]] associated with <span style="color:#FF0000">'''osteoarthritis'''</span>
 
|-
 
|-
 
|}
 
|}
Line 312: Line 312:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.67
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.67
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
Line 333: Line 333:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">increase</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''metalloproteinase 13'''</span> in <span style="color:#808000">temporomandibular joint</span> associated with <span style="color:#FF0000">'''snapping jaw'''</span> and <span style="color:#FF0000">'''metalloproteinase'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">increase</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''metalloproteinase 13'''</span>]] in [[A:temporomandibular joint|<span style="color:#808000">temporomandibular joint</span>]] associated with <span style="color:#FF0000">'''snapping jaw'''</span> and <span style="color:#FF0000">'''metalloproteinase'''</span>
 
|-
 
|-
 
|}
 
|}
Line 344: Line 344:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.58
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.58
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
Line 364: Line 364:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">overexpression</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">overexpression</span>) of <span style="color:#800000">'''Mmp-13'''</span> in <span style="color:#808000">cartilage</span> associated with <span style="color:#FF0000">'''metalloproteinase'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">overexpression</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">overexpression</span>) of [[G:17386|<span style="color:#800000">'''Mmp-13'''</span>]] in [[A:cartilage|<span style="color:#808000">cartilage</span>]] associated with <span style="color:#FF0000">'''metalloproteinase'''</span>
 
|-
 
|-
 
|}
 
|}
Line 375: Line 375:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.58
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.58
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
Line 395: Line 395:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">influence</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''collagenase'''</span> associated with <span style="color:#FF0000">'''injury'''</span> and <span style="color:#FF0000">'''keloid scars'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">influence</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''collagenase'''</span>]] associated with <span style="color:#FF0000">'''injury'''</span> and <span style="color:#FF0000">'''keloid scars'''</span>
 
|-
 
|-
 
|}
 
|}
Line 406: Line 406:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.49
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.49
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mediators of Inflammation|Mediators of Inflammation]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mediators of Inflammation|Mediators of Inflammation]]
Line 426: Line 426:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  Spec (whether) <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">increased</span>) of Spec (whether) <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''Mmp-13'''</span> in <span style="color:#808000">joints</span> associated with <span style="color:#FF0000">'''osteoarthritis'''</span>
+
|  Spec (whether) [[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">increased</span>) of Spec (whether) [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''Mmp-13'''</span>]] in [[A:joints|<span style="color:#808000">joints</span>]] associated with <span style="color:#FF0000">'''osteoarthritis'''</span>
 
|-
 
|-
 
|}
 
|}
Line 437: Line 437:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.48
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.48
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
Line 457: Line 457:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">increased</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">staining</span>) of <span style="color:#800000">'''Mmp-13'''</span> in <span style="color:#808000">joints</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">increased</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">staining</span>) of [[G:17386|<span style="color:#800000">'''Mmp-13'''</span>]] in [[A:joints|<span style="color:#808000">joints</span>]]
 
|-
 
|-
 
|}
 
|}
Line 468: Line 468:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.48
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.48
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
Line 488: Line 488:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">increased</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''collagenase'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">increased</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''collagenase'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 499: Line 499:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.45
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.45
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
Line 519: Line 519:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">overexpression</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">overexpression</span>) of <span style="color:#800000">'''metalloproteinase 13'''</span> in <span style="color:#808000">cartilage</span> associated with <span style="color:#FF0000">'''metalloproteinase'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">overexpression</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">overexpression</span>) of [[G:17386|<span style="color:#800000">'''metalloproteinase 13'''</span>]] in [[A:cartilage|<span style="color:#808000">cartilage</span>]] associated with <span style="color:#FF0000">'''metalloproteinase'''</span>
 
|-
 
|-
 
|}
 
|}
Line 530: Line 530:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.42
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.42
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arch. Oral Biol.|Arch. Oral Biol.]]
Line 551: Line 551:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">induce</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''MMP-13'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">induce</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''MMP-13'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 562: Line 562:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.41
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.41
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Annals of the Rheumatic Diseases|Annals of the Rheumatic Diseases]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Annals of the Rheumatic Diseases|Annals of the Rheumatic Diseases]]
Line 583: Line 583:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">elevated</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''Mmp13'''</span> in <span style="color:#808000">extracellular matrix</span> associated with <span style="color:#FF0000">'''metalloproteinase'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">elevated</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''Mmp13'''</span>]] in [[A:extracellular matrix|<span style="color:#808000">extracellular matrix</span>]] associated with <span style="color:#FF0000">'''metalloproteinase'''</span>
 
|-
 
|-
 
|}
 
|}
Line 594: Line 594:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.30
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.30
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Cancer|BMC Cancer]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Cancer|BMC Cancer]]
Line 615: Line 615:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">enhanced</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''MMP-13'''</span> in <span style="color:#808000">cartilage</span> associated with <span style="color:#FF0000">'''osteoarthritis'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">enhanced</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''MMP-13'''</span>]] in [[A:cartilage|<span style="color:#808000">cartilage</span>]] associated with <span style="color:#FF0000">'''osteoarthritis'''</span>
 
|-
 
|-
 
|}
 
|}
Line 626: Line 626:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.25
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.25
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
Line 646: Line 646:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">levels</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">express</span>) of <span style="color:#800000">'''matrix metalloproteinase 13'''</span> in <span style="color:#808000">cartilage</span> associated with <span style="color:#FF0000">'''metalloproteinase'''</span> and <span style="color:#FF0000">'''osteoarthritis'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">levels</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">express</span>) of [[G:17386|<span style="color:#800000">'''matrix metalloproteinase 13'''</span>]] in [[A:cartilage|<span style="color:#808000">cartilage</span>]] associated with <span style="color:#FF0000">'''metalloproteinase'''</span> and <span style="color:#FF0000">'''osteoarthritis'''</span>
 
|-
 
|-
 
|}
 
|}
Line 657: Line 657:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.25
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.25
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
Line 679: Line 679:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">induce</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''MMP-13'''</span> in <span style="color:#808000">MEFs</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">induce</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''MMP-13'''</span>]] in [[A:MEFs|<span style="color:#808000">MEFs</span>]]
 
|-
 
|-
 
|}
 
|}
Line 690: Line 690:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.19
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.19
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2009
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2009|2009]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
Line 710: Line 710:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">elevated</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''MMP-13'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">elevated</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''MMP-13'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 721: Line 721:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.18
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.18
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
Line 741: Line 741:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">elevated</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''MMP-13'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">elevated</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''MMP-13'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 752: Line 752:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.18
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.18
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
Line 772: Line 772:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">levels</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">express</span>) of <span style="color:#800000">'''MMP-13'''</span> in <span style="color:#808000">cartilage</span> associated with <span style="color:#FF0000">'''metalloproteinase'''</span> and <span style="color:#FF0000">'''osteoarthritis'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">levels</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">express</span>) of [[G:17386|<span style="color:#800000">'''MMP-13'''</span>]] in [[A:cartilage|<span style="color:#808000">cartilage</span>]] associated with <span style="color:#FF0000">'''metalloproteinase'''</span> and <span style="color:#FF0000">'''osteoarthritis'''</span>
 
|-
 
|-
 
|}
 
|}
Line 783: Line 783:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.18
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.18
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
Line 803: Line 803:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">elevated</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''MMP-13'''</span> in <span style="color:#808000">cartilage</span> associated with <span style="color:#FF0000">'''osteoarthritis'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">elevated</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:17386|<span style="color:#800000">'''MMP-13'''</span>]] in [[A:cartilage|<span style="color:#808000">cartilage</span>]] associated with <span style="color:#FF0000">'''osteoarthritis'''</span>
 
|-
 
|-
 
|}
 
|}
Line 814: Line 814:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.17
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.17
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
Line 834: Line 834:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">after</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">production</span>) of <span style="color:#800000">'''MMP-13'''</span> associated with <span style="color:#FF0000">'''rheumatoid arthritis'''</span> and <span style="color:#FF0000">'''metalloproteinase'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">after</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">production</span>) of [[G:17386|<span style="color:#800000">'''MMP-13'''</span>]] associated with <span style="color:#FF0000">'''rheumatoid arthritis'''</span> and <span style="color:#FF0000">'''metalloproteinase'''</span>
 
|-
 
|-
 
|}
 
|}
Line 845: Line 845:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.15
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.15
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
Line 865: Line 865:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Positive_regulation'''</span> (<span style="color:#000080">since</span>) of Neg (unaffected) <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">unaffected</span>) of <span style="color:#800000">'''MMP-13'''</span> in <span style="color:#808000">chondrocytes</span> associated with <span style="color:#FF0000">'''metalloproteinase'''</span>
+
[[E:Positive_regulation|<span style="color:#000080">'''Positive_regulation'''</span>]] (<span style="color:#000080">since</span>) of Neg (unaffected) [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">unaffected</span>) of [[G:17386|<span style="color:#800000">'''MMP-13'''</span>]] in [[A:chondrocytes|<span style="color:#808000">chondrocytes</span>]] associated with <span style="color:#FF0000">'''metalloproteinase'''</span>
 
|-
 
|-
 
|}
 
|}
Line 876: Line 876:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.12
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.12
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]

Latest revision as of 13:58, 20 September 2012

Context Info
Confidence 0.67
First Reported 2005
Last Reported 2010
Negated 2
Speculated 1
Reported most in Body
Documents 25
Total Number 26
Disease Relevance 13.47
Pain Relevance 9.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp13) extracellular space (Mmp13) extracellular region (Mmp13)
Golgi apparatus (Mmp13) proteinaceous extracellular matrix (Mmp13) lysosome (Mmp13)
Anatomy Link Frequency
cartilage 12
chondrocytes 6
joints 6
TMJ 4
MEFs 2
Mmp13 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 491 100.00 Very High Very High Very High
rheumatoid arthritis 431 100.00 Very High Very High Very High
Osteoarthritis 635 99.84 Very High Very High Very High
Snapping jaw 36 99.84 Very High Very High Very High
cytokine 137 94.40 High High
Arthritis 285 92.00 High High
antagonist 18 83.84 Quite High
Inflammation 213 77.60 Quite High
Kinase C 1 67.52 Quite High
fibrosis 15 59.96 Quite High
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 431 100.00 Very High Very High Very High
Keloid Scars 50 99.90 Very High Very High Very High
Osteoarthritis 671 99.84 Very High Very High Very High
Temporomandibular Joint Syndrome 36 99.84 Very High Very High Very High
Injury 38 99.30 Very High Very High Very High
Burns 5 97.04 Very High Very High Very High
Cicatrix 14 96.64 Very High Very High Very High
Hypertrophy 32 93.52 High High
Osteogenic Sarcomas 1 93.44 High High
Arthritis 305 92.00 High High

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSION: Results indicate that partial discectomy induces early-onset OA in mouse TMJ and that increased expression of Mmp-13, likely due to the elevated expression of Ddr2, may be one of the factors responsible for the early-onset OA in mouse TMJ.


Positive_regulation (increased) of Gene_expression (expression) of Mmp-13 in TMJ
1) Confidence 0.67 Published 2009 Journal Osteoarthr. Cartil. Section Body Doc Link 19230720 Disease Relevance 0.11 Pain Relevance 0
We conclude that, similar to previous observations in knee joints, the overexpression of Ddr2 and Mmp-13 may be responsible for the OA-like change in TM joints in mutant mice.
Positive_regulation (overexpression) of Gene_expression (overexpression) of Mmp-13 in joints associated with osteoarthritis
2) Confidence 0.67 Published 2007 Journal Arch. Oral Biol. Section Abstract Doc Link 17125729 Disease Relevance 0.39 Pain Relevance 0.31
Age-dependent increase of discoidin domain receptor 2 and matrix metalloproteinase 13 expression in temporomandibular joint cartilage of type IX and type XI collagen-deficient mice.
Positive_regulation (increase) of Gene_expression (expression) of metalloproteinase 13 in temporomandibular joint associated with snapping jaw and metalloproteinase
3) Confidence 0.58 Published 2007 Journal Arch. Oral Biol. Section Title Doc Link 17125729 Disease Relevance 0.36 Pain Relevance 0.35
We also found that the overexpression of matrix metalloproteinase 13 (Mmp-13) was probably due to the up-regulation of a collagen receptor, discoidin domain receptor 2 (Ddr2), which was responsible for knee cartilage degeneration in mutant mice.
Positive_regulation (overexpression) of Gene_expression (overexpression) of Mmp-13 in cartilage associated with metalloproteinase
4) Confidence 0.58 Published 2007 Journal Arch. Oral Biol. Section Abstract Doc Link 17125729 Disease Relevance 0.35 Pain Relevance 0.30
Mechanical compression of the wound may induce excessive scarring and influence the release of PGE2 and the expression of collagenases.
Positive_regulation (influence) of Gene_expression (expression) of collagenase associated with injury and keloid scars
5) Confidence 0.49 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2910481 Disease Relevance 1.96 Pain Relevance 0.27
The objective of our study was to determine whether the expression of Mmp-3, Mmp-13 and Ddr2 was increased in OA-like TM joints in mutant mice using immunohistochemistry.
Spec (whether) Positive_regulation (increased) of Spec (whether) Gene_expression (expression) of Mmp-13 in joints associated with osteoarthritis
6) Confidence 0.48 Published 2007 Journal Arch. Oral Biol. Section Abstract Doc Link 17125729 Disease Relevance 0.35 Pain Relevance 0.32
We found that the staining for Ddr2, Mmp-13 and Mmp-derived type II collagen fragments in tissue sections from 6-month-old mice was increased in TM joints of the mutant mice.
Positive_regulation (increased) of Gene_expression (staining) of Mmp-13 in joints
7) Confidence 0.48 Published 2007 Journal Arch. Oral Biol. Section Abstract Doc Link 17125729 Disease Relevance 0.33 Pain Relevance 0.32
All three hormone treatments increased the expression of procollagenase-1 in the presence of GM6001 or its control analog similarly to that shown in Fig. 1a,1b,1c.
Positive_regulation (increased) of Gene_expression (expression) of collagenase
8) Confidence 0.45 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1064880 Disease Relevance 0 Pain Relevance 0.03
We also found that the overexpression of matrix metalloproteinase 13 (Mmp-13) was probably due to the up-regulation of a collagen receptor, discoidin domain receptor 2 (Ddr2), which was responsible for knee cartilage degeneration in mutant mice.
Positive_regulation (overexpression) of Gene_expression (overexpression) of metalloproteinase 13 in cartilage associated with metalloproteinase
9) Confidence 0.42 Published 2007 Journal Arch. Oral Biol. Section Abstract Doc Link 17125729 Disease Relevance 0.35 Pain Relevance 0.30
Cleaved fragments of collagen type II again can further induce MMP-13 gene expression and result in a cycle of collagen degradation.
Positive_regulation (induce) of Gene_expression (expression) of MMP-13
10) Confidence 0.41 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2925150 Disease Relevance 0.79 Pain Relevance 0.29
An increased propensity for extracellular matrix (ECM) remodeling is suggested by elevated expression of matrix metalloproteinases (Mmp3, Mmp9 and Mmp13), urokinase-type plasminogen activator (Plau) and secreted protease inhibitors (Serpina3g, Serpin2 and Lcn2).
Positive_regulation (elevated) of Gene_expression (expression) of Mmp13 in extracellular matrix associated with metalloproteinase
11) Confidence 0.30 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2529338 Disease Relevance 0.43 Pain Relevance 0.09
These observations indicate that ALK1 signaling can induce a chondrocyte phenotype similar to that found in OA cartilage, a phenotype with simultaneous enhanced expression of matrix molecules and MMP-13.
Positive_regulation (enhanced) of Gene_expression (expression) of MMP-13 in cartilage associated with osteoarthritis
12) Confidence 0.25 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875624 Disease Relevance 0.35 Pain Relevance 0.09
Moreover, chondrocytes in OA cartilage express high levels of matrix metalloproteinase 13 (MMP-13), the enzyme most potently degrading type II collagen [6].
Positive_regulation (levels) of Gene_expression (express) of matrix metalloproteinase 13 in cartilage associated with metalloproteinase and osteoarthritis
13) Confidence 0.25 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875624 Disease Relevance 1.02 Pain Relevance 0.51
To induce MMP-13 expression MEFs were treated for 5 hrs with 5 ng/ml PMA.


Positive_regulation (induce) of Gene_expression (expression) of MMP-13 in MEFs
14) Confidence 0.19 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2781169 Disease Relevance 0.22 Pain Relevance 0.05
In addition, overexpression of constitutive active ALK5 (Smad2/3) results in increased expression of aggrecan while constitutive ALK1 (Smad1/5/8) expression leads to elevated expression of MMP-13.
Positive_regulation (elevated) of Gene_expression (expression) of MMP-13
15) Confidence 0.18 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875624 Disease Relevance 0.25 Pain Relevance 0.06
Blocking ALK5 expression using siRNA resulted in elevated expression of MMP-13 [85].
Positive_regulation (elevated) of Gene_expression (expression) of MMP-13
16) Confidence 0.18 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875624 Disease Relevance 0.26 Pain Relevance 0.06
Moreover, chondrocytes in OA cartilage express high levels of matrix metalloproteinase 13 (MMP-13), the enzyme most potently degrading type II collagen [6].
Positive_regulation (levels) of Gene_expression (express) of MMP-13 in cartilage associated with metalloproteinase and osteoarthritis
17) Confidence 0.18 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875624 Disease Relevance 1.02 Pain Relevance 0.51
In conclusion, loss of the Smad2/3 signaling and relatively enhanced Smad1/5/8 signaling can explain the enigmatic observation in OA cartilage of elevated expression of both matrix molecules and proteolytic enzymes, like MMP-13.
Positive_regulation (elevated) of Gene_expression (expression) of MMP-13 in cartilage associated with osteoarthritis
18) Confidence 0.17 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875624 Disease Relevance 0.79 Pain Relevance 0.17
In our studies we observed maximal MMP-13 production (mean ± SEM) in RA FLS 24 hours after stimulation with IL-1?
Positive_regulation (after) of Gene_expression (production) of MMP-13 associated with rheumatoid arthritis and metalloproteinase
19) Confidence 0.15 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888198 Disease Relevance 0.61 Pain Relevance 1.04
However, not all MMPs were stimulated by gal-3 in chondrocytes, since collagenase-3 (MMP-13) was unaffected (data not shown).
Positive_regulation (since) of Neg (unaffected) Gene_expression (unaffected) of MMP-13 in chondrocytes associated with metalloproteinase
20) Confidence 0.12 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860078 Disease Relevance 0.33 Pain Relevance 0.24

[edit] General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox