INT140869

Context Info Confidence 0.04 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0.15 Pain Relevance 0.37

cell proliferation (Gdnf) extracellular space (Gdnf) extracellular region (Gdnf) nucleolus (Trib3) nucleus (Trib3) enzyme binding (Trib3)

Anatomy Link Frequency glial cell 2 Gdnf (Rattus norvegicus) Trib3 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Spinal cord 6 83.04 Dorsal horn 8 81.44 dorsal rhizotomy 2 66.32 projection neuron 4 31.36 Dorsal horn neuron 2 25.00 Pain 2 25.00

Disease Link Frequency Relevance Heat Nervous System Injury 4 75.00 Nociception 6 32.32

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

RET (for "rearranged during transfection") is a transmembrane tyrosine kinase signaling receptor for members of the glial cell line-derived neurotrophic factor (GDNF) family of ligands.

GDNF Binding (receptor) of kinase in glial cell

1) Confidence 0.04 Published 2007 Journal J. Comp. Neurol. Section Abstract Doc Link 17183535 Disease Relevance 0.07 Pain Relevance 0.18

RET (for "rearranged during transfection") is a transmembrane tyrosine kinase signaling receptor for members of the glial cell line-derived neurotrophic factor (GDNF) family of ligands.

GDNF Binding (receptor) of kinase in glial cell

2) Confidence 0.04 Published 2007 Journal J. Comp. Neurol. Section Abstract Doc Link 17183535 Disease Relevance 0.07 Pain Relevance 0.18

General Comments

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