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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Dpysl2) cytosol (Dpysl2) mitochondrion (Dpysl2)
cytoskeleton organization (Dpysl2) protein complex (Dpysl2) cytoplasm (Dpysl2)
Dpysl2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
sodium channel 1 99.64 Very High Very High Very High
lacosamide 12 98.06 Very High Very High Very High
Neuropathic pain 1 95.64 Very High Very High Very High
headache 1 44.40 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 1 95.64 Very High Very High Very High
Diabetes Mellitus 1 94.96 High High
Epilepsy 1 93.48 High High
Convulsion 1 64.96 Quite High
Dizziness 1 45.28 Quite Low
Headache 1 44.40 Quite Low
Vomiting 1 43.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lacosamide appears to have a dual mode of action: selective enhancement of sodium channel inactivation and modulation of collapsin response mediator protein-2.
Regulation (modulation) of mediator protein-2 associated with sodium channel and lacosamide
1) Confidence 0.04 Published 2007 Journal Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics Section Abstract Doc Link 17199030 Disease Relevance 0.35 Pain Relevance 0.43

General Comments

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