INT141426

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ADCY1) small molecule metabolic process (ADCY1) plasma membrane (ADCY1)
nucleus (ADCY1) GTPase activity (ADCY1) transmembrane transport (ADCY1)
ANTXRL (Homo sapiens)
ADCY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
mu opioid receptor 1 99.64 Very High Very High Very High
opioid receptor 2 67.44 Quite High
MU agonist 1 47.28 Quite Low
Enkephalin 1 43.92 Quite Low
Potency 1 34.00 Quite Low
Opioid 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Bordatella Infection 4 100.00 Very High Very High Very High
Glioma 1 70.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chronic activation of mu-opioid receptors, which couple to pertussis toxin-sensitive Galphai/o proteins to inhibit adenylyl cyclase (AC), leads to a compensatory sensitization of AC.
pertussis toxin Negative_regulation (inhibit) of cyclase associated with bordatella infection and mu opioid receptor
1) Confidence 0.00 Published 2006 Journal J. Neurochem. Section Abstract Doc Link 17230639 Disease Relevance 0.41 Pain Relevance 0.11

General Comments

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