INT141676

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (OPRM1) endoplasmic reticulum (OPRM1) plasma membrane (OPRM1)
signal transducer activity (OPRM1)
OPRM1 (Homo sapiens)
Ltp (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 4 100.00 Very High Very High Very High
agonist 1 100.00 Very High Very High Very High
antagonist 1 99.28 Very High Very High Very High
opiate 7 98.24 Very High Very High Very High
Morphine 6 94.32 High High
withdrawal 3 85.56 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, DAMGO, a mu-opioid receptor (MOR) agonist, could restore the reduced LTP, and CTOP, a MOR antagonist, could block the restoration in rats dependent on both opiates, showing that MOR is functional under such conditions.
MOR Positive_regulation (restore) of LTP associated with antagonist, agonist, opiate and opioid receptor
1) Confidence 0.04 Published 2007 Journal Neuropsychopharmacology Section Abstract Doc Link 17251910 Disease Relevance 0 Pain Relevance 1.46

General Comments

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