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Context Info
Confidence 0.39
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.11
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Accn3) cytoplasm (Accn3)
Anatomy Link Frequency
masseter 2
Accn3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ASIC 23 100.00 Very High Very High Very High
qutenza 15 99.36 Very High Very High Very High
trigeminal ganglion 24 96.84 Very High Very High Very High
Pain 11 91.28 High High
calcitonin gene related peptide 1 86.76 High High
substance P 1 85.44 High High
nociceptor 19 83.16 Quite High
Root ganglion neuron 2 82.08 Quite High
Angina 1 76.72 Quite High
Inflammation 6 76.52 Quite High
Disease Link Frequency Relevance Heat
Nociception 24 98.34 Very High Very High Very High
Ganglion Cysts 34 96.84 Very High Very High Very High
Pain 5 91.28 High High
Cv General 3 Under Development 1 76.72 Quite High
INFLAMMATION 3 76.52 Quite High
Ischemic Heart Disease 1 72.12 Quite High
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Myalgia 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AA potentiates ASIC activation by a direct mechanism, because inhibition of AA metabolism had no effect on potentiation, and potentiation of single ASIC2a channels could be observed in cell-free patches.
Positive_regulation (potentiates) of Positive_regulation (activation) of ASIC associated with asic
1) Confidence 0.39 Published 2007 Journal Neuroscience Section Abstract Doc Link 17258862 Disease Relevance 0.37 Pain Relevance 0.44
Almost all the masseter afferents isolated from the TG expressed significant amounts of at least one of the putative "nociceptive" ion channels we examined in this study; capsaicin activated TRPV1 channels, acid activated ASIC-3-like channels or ATP activated P2X3-like channels.
Positive_regulation (activated) of Positive_regulation (activated) of ASIC-3-like in masseter associated with nociception, qutenza, trigeminal ganglion and asic
2) Confidence 0.29 Published 2005 Journal Mol Pain Section Body Doc Link PMC1283980 Disease Relevance 0.74 Pain Relevance 0.75

General Comments

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