INT142087

Context Info Confidence 0.40 First Reported 2007 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 5 Total Number 6 Disease Relevance 0.33 Pain Relevance 0.79

cytosol (SNRPG) nucleoplasm (SNRPG) mRNA processing (SNRPG) RNA binding (SNRPG) nucleus (SNRPG)

Anatomy Link Frequency SMG 2 duct 1 SNRPG (Homo sapiens)

Pain Link Frequency Relevance Heat qutenza 16 94.96 antagonist 2 93.00 agonist 2 81.96

Disease Link Frequency Relevance Heat Frailty 4 95.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

On the rabbit model of microvascular transfer of SMG, phenylephrine(10(-7) mol/L) was infused into SMG through the Wharton's duct.

Gene_expression (transfer) of SMG in duct

1) Confidence 0.40 Published 2007 Journal Beijing Da Xue Xue Bao Section Abstract Doc Link 17304317 Disease Relevance 0.07 Pain Relevance 0.09

The secretion of transferred SMG was significantly increased without significant changes of cardiovascular function.

Gene_expression (transferred) of SMG

2) Confidence 0.31 Published 2007 Journal Beijing Da Xue Xue Bao Section Abstract Doc Link 17304317 Disease Relevance 0.07 Pain Relevance 0.09

These results provided a experimental basis for deeply understanding of secretion mechanism of normal and transferred SMG, and effective regulation of secretion of the transferred SMG.

Gene_expression (transferred) of SMG

3) Confidence 0.31 Published 2007 Journal Beijing Da Xue Xue Bao Section Abstract Doc Link 17304317 Disease Relevance 0.10 Pain Relevance 0.07

These results provided a experimental basis for deeply understanding of secretion mechanism of normal and transferred SMG, and effective regulation of secretion of the transferred SMG.

Gene_expression (transferred) of SMG

4) Confidence 0.31 Published 2007 Journal Beijing Da Xue Xue Bao Section Abstract Doc Link 17304317 Disease Relevance 0.09 Pain Relevance 0.07

We hypothesized that VR1 exists in the human submandibular gland (SMG) and is involved in regulating salivary secretion.

Gene_expression (exists) of SMG in SMG

5) Confidence 0.23 Published 2010 Journal J. Dent. Res. Section Abstract Doc Link 20371865 Disease Relevance 0 Pain Relevance 0.20

These findings indicated that a functional VR1 is expressed in the human SMG and is involved in regulating salivary secretion by mediating AQP5 trafficking.

Gene_expression (expressed) of SMG in SMG

6) Confidence 0.23 Published 2010 Journal J. Dent. Res. Section Abstract Doc Link 20371865 Disease Relevance 0 Pain Relevance 0.26

General Comments

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