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Context Info
Confidence 0.57
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.93
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (PGF) signal transduction (PGF) extracellular region (PGF)
cell-cell signaling (PGF)
Anatomy Link Frequency
skeletal muscle 2
PGF (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 13 99.44 Very High Very High Very High
Paracetamol 4 96.72 Very High Very High Very High
cINOD 2 55.76 Quite High
COX2 1 25.00 Low Low
cOX1 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 14 99.44 Very High Very High Very High
Volume Depletion And Dehydration 1 74.24 Quite High
Increased Venous Pressure Under Development 1 41.04 Quite Low
Myocardial Infarction 1 30.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The inconsistent and low levels of expression of the intron 1-retaining COX-1 variants suggest that these variants are not likely responsible for the inhibition of PGF(2alpha) production and skeletal muscle protein synthesis after resistance exercise by ibuprofen and acetaminophen.
Negative_regulation (inhibition) of Gene_expression (production) of PGF in skeletal muscle associated with paracetamol
1) Confidence 0.57 Published 2007 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 17322116 Disease Relevance 0 Pain Relevance 0.22
In animal models, expression of both PGD and PGF synthases declines during acute inflammation, only to rise again during the resolution phase, suggesting their possible role in resolving inflammation.
Negative_regulation (declines) of Gene_expression (expression) of PGF associated with inflammation
2) Confidence 0.57 Published 2009 Journal J. Investig. Med. Section Abstract Doc Link 19240648 Disease Relevance 0.93 Pain Relevance 0.46

General Comments

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