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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Src, Arrb2) nucleus (Src, Arrb2) plasma membrane (Src, Arrb2)
transport (Arrb2) mitochondrion (Src) intracellular (Arrb2)
Src (Mus musculus)
Arrb2 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 6 95.68 Very High Very High Very High
Root ganglion neuron 2 75.00 Quite High
mu opioid receptor 1 75.00 Quite High
antagonist 1 67.56 Quite High
Potency 1 53.20 Quite High
Enkephalin 1 51.80 Quite High
Morphine 2 49.92 Quite Low
Pain 2 25.00 Low Low
nociceptor 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We propose that beta-arrestin2 is required to target c-Src to constitutively active mu receptors, resulting in their internalization, providing another dimension to the complex role of beta-arrestin2 and c-Src in G-protein-coupled receptor function.
Src Binding (target) of beta-arrestin2
1) Confidence 0.27 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17494695 Disease Relevance 0.07 Pain Relevance 0.37

General Comments

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