INT144244

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TNF, NFKBIA) intracellular (TNF) enzyme binding (NFKBIA)
extracellular matrix organization (TNF) cytoplasm (NFKBIA) cytosol (NFKBIA)
TNF (Homo sapiens)
NFKBIA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 1 89.20 High High
cytokine 7 85.36 High High
Inflammatory mediators 1 51.52 Quite High
endometriosis 1 48.76 Quite Low
Pain 1 45.36 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 89.20 High High
Endometriosis 5 75.00 Quite High
Cancer 1 60.64 Quite High
Sleep Initiation And Maintenance Disorders 1 46.08 Quite Low
Pain 1 45.36 Quite Low
Disease 1 44.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Western blot analyses revealed that hCG-A impaired TNF-alpha-mediated phosphorylation and degradation of the inhibitor IkappaBalpha suggesting that the hormone may reduce nuclear import of NF-kappaB by stabilizing its inhibitor.
TNF-alpha Positive_regulation (mediated) of Protein_catabolism (degradation) of IkappaBalpha
1) Confidence 0.28 Published 2007 Journal Mol. Hum. Reprod. Section Abstract Doc Link 17525069 Disease Relevance 0.34 Pain Relevance 0.22

General Comments

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