INT144367

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Context Info
Confidence 0.11
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Th) cytoplasm (Th) cell proliferation (Gdnf)
cytosol (Th) extracellular space (Gdnf) extracellular region (Gdnf)
Anatomy Link Frequency
ventral 2
Gdnf (Mus musculus)
Th (Mus musculus)
Pain Link Frequency Relevance Heat
cocaine 2 100.00 Very High Very High Very High
addiction 6 99.36 Very High Very High Very High
Ventral tegmentum 1 99.32 Very High Very High Very High
cytokine 1 89.32 High High
Morphine 6 84.88 Quite High
Dopamine 1 37.60 Quite Low
Nucleus accumbens 1 35.76 Quite Low
Disease Link Frequency Relevance Heat
Drug Dependence 6 99.36 Very High Very High Very High
Necrosis 2 97.60 Very High Very High Very High
Cancer 2 97.24 Very High Very High Very High
Targeted Disruption 1 49.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GDNF inhibits the cocaine-induced upregulation of tyrosine hydroxylase activity in the ventral tegmental area and blocks behavioral responses to cocaine.
GDNF Negative_regulation (inhibits) of Positive_regulation (upregulation) of tyrosine hydroxylase in ventral associated with ventral tegmentum and cocaine
1) Confidence 0.11 Published 2007 Journal J. Pharmacol. Sci. Section Abstract Doc Link 17538232 Disease Relevance 0.77 Pain Relevance 0.70

General Comments

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