INT144392

From wiki-pain
Revision as of 13:31, 21 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.83
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nos2) signal transduction (Nos2) extracellular space (Nos2)
oxidoreductase activity (Nos2) peroxisome (Nos2) nucleus (Nos2)
Nos2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 1 98.24 Very High Very High Very High
Hyperalgesia 2 97.32 Very High Very High Very High
Endogenous opioid 1 96.28 Very High Very High Very High
Inflammation 14 95.68 Very High Very High Very High
hypoalgesia 1 95.12 Very High Very High Very High
narcan 2 82.44 Quite High
antagonist 1 82.04 Quite High
opioid receptor 2 81.60 Quite High
Thermal hyperalgesia 4 76.00 Quite High
cytokine 5 70.32 Quite High
Disease Link Frequency Relevance Heat
Osteogenic Sarcomas 5 98.16 Very High Very High Very High
INFLAMMATION 15 97.88 Very High Very High Very High
Hyperalgesia 6 97.32 Very High Very High Very High
Stress 4 95.16 Very High Very High Very High
Hypoalagesia 1 95.12 Very High Very High Very High
Aging 1 91.80 High High
Bone Cancer 1 75.00 Quite High
Inflammatory Pain 1 69.16 Quite High
Myocardial Infarction 67 68.48 Quite High
Apoptosis 9 66.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This effect was due to down-regulation of iNOS mRNA and suppression of iNOS proteins, i.e., blueberry extract may inhibit one of the primary steps in the inflammatory stress pathway [41].
Negative_regulation (down) of Negative_regulation (regulation) of iNOS associated with stress and inflammation
1) Confidence 0.42 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2693933 Disease Relevance 0.86 Pain Relevance 0.20
The selective inhibitor of eNOS L-NIO, but not the inhibitors of nNOS (N-omega-propyl-L-arginine) or iNOS (1400w), blocked the effect of loperamide on osteosarcoma-induced hyperalgesia and also the endogenous opioid peripheral hypoalgesia that appears during the initial stages of the development of this osteosarcoma.
Negative_regulation (inhibitor) of Negative_regulation (inhibitors) of iNOS associated with hyperalgesia, endogenous opioid, hypoalgesia and osteogenic sarcomas
2) Confidence 0.30 Published 2007 Journal Neuropharmacology Section Abstract Doc Link 17543351 Disease Relevance 0.97 Pain Relevance 1.05

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox