INT144475

Context Info Confidence 0.17 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.58 Pain Relevance 0.33

mitochondrion (Sod2) oxidoreductase activity (Sod2) mitochondrion organization (Sod2) DNA binding (Sod2) response to stress (Sod2) cytoplasm (Sod2)

Sod2 (Mus musculus)

Pain Link Frequency Relevance Heat Chronic pancreatitis 3 94.96 alcohol 1 89.88

Disease Link Frequency Relevance Heat Pancreatitis 4 94.96 Exocrine Pancreatic Insufficiency 3 92.24 Alcoholic Pancreatitis 3 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Several enzymes involved in the degradation of reactive oxidants and xenobiotics, such as glutathione-S-transferase P1 (GSTP1) and manganese-superoxide dismutase (MnSOD) reveal functional polymorphisms that affect the antioxidative capacity and may therefore modulate the development of chronic pancreatitis and long-term complications like endocrine and exocrine pancreatic insufficiency.

Protein_catabolism (degradation) of manganese-superoxide dismutase associated with exocrine pancreatic insufficiency and chronic pancreatitis

1) Confidence 0.17 Published 2007 Journal Mutagenesis Section Abstract Doc Link 17548864 Disease Relevance 0.58 Pain Relevance 0.33

General Comments

This test has worked.