INT144907

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Context Info
Confidence 0.53
First Reported 2002
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.57
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RAC3) plasma membrane (RAC3) GTPase activity (RAC3)
cytoplasm (RAC3)
Anatomy Link Frequency
muscle 1
RAC3 (Homo sapiens)
Pain Link Frequency Relevance Heat
sodium channel 4 100.00 Very High Very High Very High
antagonist 3 100.00 Very High Very High Very High
tetrodotoxin 1 100.00 Very High Very High Very High
dorsal root ganglion 3 96.60 Very High Very High Very High
agonist 5 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Poisoning 1 99.60 Very High Very High Very High
Ganglion Cysts 3 96.60 Very High Very High Very High
Paralysis 2 81.64 Quite High
Syndrome 1 53.28 Quite High
Reprotox - General 1 1 49.52 Quite Low
Hypersensitivity 6 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Adenocarcinoma 1 5.00 Very Low Very Low Very Low
Wrinkles 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Also, the behavioral effects of crotamine intoxication were compared with those of a muscle-selective sodium channel antagonist mu-CgTx-GIIIA, and other sodium-acting toxins such as tetrodotoxin alpha- and beta-pompilidotoxins, sea anemone toxin BcIII, spider toxin Tx2-6.
Gene_expression (those) of anemone toxin BcIII in muscle associated with tetrodotoxin, antagonist, sodium channel and poisoning
1) Confidence 0.53 Published 2007 Journal Toxicon Section Abstract Doc Link 17588630 Disease Relevance 0.57 Pain Relevance 0.43
We then assayed similarly expression levels for nuclear coactivators AIB1 [16], CBP [17], p300 [18], p/CIP [19], RAC3 [20], RIP140 [21], SRC1 [22], TIF1 [23], TIF2 [24] and TRIP1 [25].
Gene_expression (expression) of RAC3
2) Confidence 0.21 Published 2002 Journal BMC Pharmacol Section Body Doc Link PMC113761 Disease Relevance 0 Pain Relevance 0

General Comments

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