INT146931

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Context Info
Confidence 0.44
First Reported 2006
Last Reported 2007
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.22
Pain Relevance 2.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CAP1) cell morphogenesis (CAP1) plasma membrane (CAP1)
cytoskeleton organization (CAP1) cytoplasm (CAP1)
Anatomy Link Frequency
trunk 1
afferent neurons 1
CAP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 175 100.00 Very High Very High Very High
c fibre 32 88.40 High High
Central nervous system 4 78.64 Quite High
unmyelinated 4 38.08 Quite Low
depression 4 26.20 Quite Low
Action potential 20 5.00 Very Low Very Low Very Low
agonist 14 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
sodium channel 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 3 76.44 Quite High
Injury 1 73.68 Quite High
Ganglion Cysts 2 66.08 Quite High
Depression 4 26.20 Quite Low
Shock 6 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We next examined the effects of Cap on the activity of P-glycoprotein (P-gp) found on transcellular transporters.
Spec (examined) Regulation (effects) of Cap associated with qutenza
1) Confidence 0.44 Published 2007 Journal Biol. Pharm. Bull. Section Abstract Doc Link 17917278 Disease Relevance 0.15 Pain Relevance 1.08
Such A-type BRs are likely typical of a broad association for cranial visceral afferent neurons with CAP sensitivity.
Regulation (afferent neurons) of CAP in afferent neurons associated with qutenza
2) Confidence 0.06 Published 2006 Journal J Negat Results Biomed Section Body Doc Link PMC1481593 Disease Relevance 0.07 Pain Relevance 0.86
Thus, at concentrations of CAP that interrupted C-wave axonal transmission in the ADN trunk, the responses of regularly discharging BRs to pressure were unaffected.
Neg (unaffected) Regulation (unaffected) of CAP in trunk associated with qutenza
3) Confidence 0.06 Published 2006 Journal J Negat Results Biomed Section Body Doc Link PMC1481593 Disease Relevance 0 Pain Relevance 0.64

General Comments

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