INT147033

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 1.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Sds, Accn3) mitochondrion (Sds) lyase activity (Sds)
plasma membrane (Accn3) cellular_component (Sds) cellular amino acid metabolic process (Sds)
Anatomy Link Frequency
neurons 2
Sds (Rattus norvegicus)
Accn3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spinal dorsal horn 6 100.00 Very High Very High Very High
ASIC 5 100.00 Very High Very High Very High
Pain 5 99.28 Very High Very High Very High
central sensitization 3 98.96 Very High Very High Very High
c fibre 1 95.44 Very High Very High Very High
Antinociceptive 1 90.80 High High
Inflammation 4 82.72 Quite High
Dorsal horn neuron 1 75.00 Quite High
Stimulus evoked pain 1 75.00 Quite High
IPN 1 71.04 Quite High
Disease Link Frequency Relevance Heat
Pain 3 99.28 Very High Very High Very High
Nociception 1 98.24 Very High Very High Very High
Hypersensitivity 3 97.48 Very High Very High Very High
Inflammatory Pain 2 75.00 Quite High
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Together, our results reveal that increased ASIC activity in SDH neurons promotes pain by central sensitization.
Positive_regulation (increased) of SDH Binding (activity) of ASIC in neurons associated with pain, central sensitization, spinal dorsal horn and asic
1) Confidence 0.13 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17928456 Disease Relevance 0.73 Pain Relevance 1.23

General Comments

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