INT147040

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Context Info
Confidence 0.07
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.95
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hmbs, Nppa) cytoplasm (Hmbs, Nppa) extracellular region (Nppa)
Anatomy Link Frequency
neurons 1
RTN 1
Hmbs (Rattus norvegicus)
Nppa (Rattus norvegicus)
Pain Link Frequency Relevance Heat
c fibre 10 90.20 High High
Disease Link Frequency Relevance Heat
Porphyria 12 100.00 Very High Very High Very High
Sleep Disorders 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Muscimol injection into the solitary tract nucleus, commissural part, reduced inhibition of PND and RTN by PBG (73%), blocked activation of PND and RTN by CB stimulation (cyanide) but had no effect on inhibition of PND and RTN by lung inflation.
PBG Negative_regulation (inhibition) of PND in RTN associated with porphyria
1) Confidence 0.07 Published 2007 Journal J. Neurophysiol. Section Abstract Doc Link 17928558 Disease Relevance 0.43 Pain Relevance 0.25
Bilateral injections of muscimol into interstitial solitary tract nucleus (NTS) reduced the inhibition of PND and RTN by PBG (53%), blocked the inhibitory effects of lung inflation but did not change the activation of PND and RTN neurons by CB stimulation.
PBG Negative_regulation (inhibition) of PND in neurons associated with porphyria
2) Confidence 0.05 Published 2007 Journal J. Neurophysiol. Section Abstract Doc Link 17928558 Disease Relevance 0.51 Pain Relevance 0.29

General Comments

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