INT147675

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.07

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signal transduction (GRP) extracellular space (GRP) extracellular region (GRP)
nucleus (Atf2) intracellular (Atf2) DNA binding (Atf2)
Anatomy Link Frequency
SCN 2
Atf2 (Mus musculus)
GRP (Homo sapiens)
Pain Link Frequency Relevance Heat
tetrodotoxin 1 74.96 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we tested the putative role of GRP as an intra-SCN light signal at the behavioral and cellular levels, and we also tested whether GRP actions are dependent on activation of the cAMP response element-binding protein (CREB) pathway and Per1.
Spec (853) Positive_regulation (activation) of cAMP response element-binding protein in SCN Spec (whether) Positive_regulation (dependent) of GRP
1) Confidence 0.04 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17978049 Disease Relevance 0 Pain Relevance 0.07

General Comments

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