INT148418

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Context Info
Confidence 0.12
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 1.53
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (Ugt1a7c) endoplasmic reticulum (Ugt1a7c)
Anatomy Link Frequency
monocytes 2
lymphocytes 1
Ugt1a7c (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 10 98.24 Very High Very High Very High
Acute pain 2 75.00 Quite High
Inflammation 15 52.24 Quite High
Pain 2 25.00 Low Low
rheumatoid arthritis 33 8.88 Low Low
ischemia 6 5.00 Very Low Very Low Very Low
psoriasis 6 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
endometriosis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Vasculitis 264 89.60 High High
Shock 4 81.52 Quite High
Pain 2 75.00 Quite High
Targeted Disruption 81 71.36 Quite High
Necrosis 3 61.04 Quite High
Cancer 3 60.68 Quite High
Stress 10 44.60 Quite Low
INFLAMMATION 15 30.00 Quite Low
Rheumatoid Arthritis 33 8.88 Low Low
Systemic Lupus Erythematosus 36 8.60 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regarding effects on cytokines, no significant changes were detected in the amount of Interferon-gamma (IFNgamma) and Interlukin-10 (IL-10) produced by lymphocytes obtained from the spleens of any of the shocked mice.
Gene_expression (produced) of Interlukin-10 in lymphocytes associated with cytokine
1) Confidence 0.12 Published 2007 Journal Immunopharmacol Immunotoxicol Section Abstract Doc Link 18075858 Disease Relevance 0.40 Pain Relevance 0.25
We previously reported that G0S2 was primarily expressed in monocytes, whereas Amphiregulin was expressed in both monocytes, T cells and B cells by performing RT–PCR on multiple-tissue cDNA panels (MTC) from Clontech (Palo Alto, CA).5 To determine whether EGR1, HBD, TVAS10, IL1R2, and calgranulin C are also expressed in particular human blood cells, we conducted similar experiments.
Gene_expression (expressed) of TVAS10 in monocytes
2) Confidence 0.01 Published 2008 Journal DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes Section Body Doc Link PMC2575881 Disease Relevance 0.38 Pain Relevance 0.06
Only EGR1 and TVAS10 were expressed in activated CD8+ T (lane 9) cells.
Gene_expression (expressed) of TVAS10
3) Confidence 0.01 Published 2008 Journal DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes Section Body Doc Link PMC2575881 Disease Relevance 0.34 Pain Relevance 0
EGR1, TVAS10, IL1R2, and calgranulin C were expressed in resting CD8+ T cells (T-suppressor/cytotoxic; lane 2) and monocytes (lane 4).
Gene_expression (expressed) of TVAS10 in monocytes
4) Confidence 0.01 Published 2008 Journal DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes Section Body Doc Link PMC2575881 Disease Relevance 0.41 Pain Relevance 0

General Comments

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