INT148437

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Context Info
Confidence 0.32
First Reported 2005
Last Reported 2007
Negated 2
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.90
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bdnf, Ngf) signal transduction (Ngf) extracellular space (Ngf)
aging (Ngf) cytoplasmic membrane-bounded vesicle (Bdnf) molecular_function (Ngf)
Anatomy Link Frequency
neurons 1
spinal cord 1
Bdnf (Rattus norvegicus)
Ngf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 101 100.00 Very High Very High Very High
qutenza 52 97.08 Very High Very High Very High
Calcitonin gene-related peptide 96 96.64 Very High Very High Very High
Spinal cord 9 96.56 Very High Very High Very High
trigeminal ganglion 59 95.92 Very High Very High Very High
anesthesia 1 83.80 Quite High
Inflammation 6 81.76 Quite High
Dorsal horn 1 81.76 Quite High
neurotrophin 3 1 66.32 Quite High
dorsal root ganglion 12 57.56 Quite High
Disease Link Frequency Relevance Heat
Frailty 9 99.48 Very High Very High Very High
Ganglion Cysts 73 95.92 Very High Very High Very High
Injury 28 94.48 High High
Pressure And Volume Under Development 2 93.40 High High
INFLAMMATION 5 81.76 Quite High
Nociception 8 5.00 Very Low Very Low Very Low
Hyperalgesia 7 5.00 Very Low Very Low Very Low
Headache 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, a combination of BDNF and GDNF (but not with NT-3 or NGF) given either 60 or 90 min after SCI significantly reduced the motor dysfunction and spinal cord pathology at 5 h.
BDNF Neg (not) Binding (combination) of NGF in spinal cord associated with frailty and spinal cord
1) Confidence 0.32 Published 2007 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 18077567 Disease Relevance 1.14 Pain Relevance 0.40
We have also illustrated that chronic application of NGF or GDNF, but not BDNF (except at high concentrations, and to a much lesser degree), increases CAP-evoked CGRP release from TG neurons in vitro.
BDNF Neg (not) Binding (application) of NGF in neurons associated with qutenza, nerve growth factor, trigeminal ganglion and calcitonin gene-related peptide
2) Confidence 0.16 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.76 Pain Relevance 0.77

General Comments

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