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Context Info
Confidence 0.46
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Calca, Usf2) extracellular space (Calca) aging (Calca)
extracellular region (Calca) intracellular (Calca) DNA binding (Usf2)
Calca (Rattus norvegicus)
Usf2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 8 100.00 Very High Very High Very High
Trigeminal ganglion neurons 4 96.08 Very High Very High Very High
Migraine 2 94.60 High High
Neuropeptide 1 88.72 High High
Disease Link Frequency Relevance Heat
Ganglion Cysts 4 95.76 Very High Very High Very High
Headache 2 94.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous in vitro studies demonstrated that upstream stimulatory factor (USF) 1 and USF2 bind to the CGRP neuroendocrine-specific 18-bp enhancer, yet discrepant overexpression results in cell lines, and the ubiquitous nature of the USF cast doubts about its role.
CGRP Binding (bind) of USF2 associated with calcitonin gene-related peptide
1) Confidence 0.46 Published 2008 Journal J. Biol. Chem. Section Abstract Doc Link 18167349 Disease Relevance 0.42 Pain Relevance 0.64

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