INT148894

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Context Info
Confidence 0.47
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0.99
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cellular_component (Cytl1)
Cytl1 (Mus musculus)
Cytl1 - C17T (1)
Pain Link Frequency Relevance Heat
drug abuse 1 99.76 Very High Very High Very High
mu opioid receptor 2 96.68 Very High Very High Very High
addiction 4 94.52 High High
opiate 2 94.12 High High
Opioid receptor 1 1 92.92 High High
Opioid 3 86.08 High High
Inflammation 36 70.88 Quite High
cytokine 30 62.16 Quite High
rheumatoid arthritis 3 25.44 Quite Low
imagery 27 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Dependence 1 99.76 Very High Very High Very High
Death 9 97.04 Very High Very High Very High
Opiate Addiction 4 94.52 High High
Apoptosis 78 83.68 Quite High
INFLAMMATION 51 70.88 Quite High
Cancer 15 63.52 Quite High
Disease 9 31.40 Quite Low
Rheumatoid Arthritis 3 25.44 Quite Low
Macrophage Activation Syndrome 3 24.44 Low Low
Necrosis 6 17.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies from our and other laboratories have established high-affinity binding of cyt c with PS [82].
cyt Binding (binding) of
1) Confidence 0.47 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2634966 Disease Relevance 0.20 Pain Relevance 0
Given that positively charged cyt c readily interacts with negatively charged surfaces we assumed that SWCNT coated with anionic PS would effectively bind to cyt c.
cyt Binding (interacts) of
2) Confidence 0.47 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2634966 Disease Relevance 0.23 Pain Relevance 0.10
After the coating, binding of positively-charged cyt c was likely associated with abundant negatively-charged PS.
cyt Binding (binding) of
3) Confidence 0.35 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2634966 Disease Relevance 0.20 Pain Relevance 0
Two of these, C17T and A118G, have been reported to be associated with substance abuse.
C17T (C17T) Binding (associated) of associated with drug abuse
4) Confidence 0.00 Published 2007 Journal J. Integr. Neurosci. Section Abstract Doc Link 18181266 Disease Relevance 0.36 Pain Relevance 0.68

General Comments

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