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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.23
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (PITX2) transcription factor binding (PITX2)
PITX2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 94.52 High High
cytokine 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Apoptosis 9 98.24 Very High Very High Very High
INFLAMMATION 1 94.00 High High
Cancer 7 90.48 High High
Parkinson's Disease 1 80.92 Quite High
Necrosis 1 76.48 Quite High
Hepatocellular Cancer 1 75.00 Quite High
Death 1 65.08 Quite High
Genomic Instability 1 36.00 Quite Low
Aging 1 31.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although further studies are needed to prove that an increased expression of Egr-1 by PTX-2 directly leads to NAG-1 induction and then apoptosis induction in p53-deficient Hep3B cells, the results of this study suggest that PTX-2 may be a good candidate for the development of a potential anti-tumorigenic agent in p53-deficient tumors.
Positive_regulation (increased) of Gene_expression (expression) of PTX-2 associated with cancer and apoptosis
1) Confidence 0.05 Published 2008 Journal Oncol. Rep. Section Abstract Doc Link 18202802 Disease Relevance 1.23 Pain Relevance 0.19

General Comments

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