INT149312

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.27
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (KCNF1) transmembrane transport (KCNF1)
Anatomy Link Frequency
pore 1
KCNF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 95.24 Very High Very High Very High
Migraine 1 84.96 Quite High
Pain 1 83.84 Quite High
ischemia 1 83.60 Quite High
Spinal cord 1 83.24 Quite High
Multiple sclerosis 1 79.52 Quite High
potassium channel 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Sepsis 1 89.56 High High
Urinary Tract Disease 1 89.12 High High
Cervical Cancer 1 88.28 High High
Diabetes Mellitus 1 87.60 High High
Hypertension 1 87.20 High High
Headache 1 84.96 Quite High
Schizophrenia 1 84.56 Quite High
Pain 1 83.84 Quite High
Spinal Cord Ischemia 1 83.60 Quite High
Brain Tumor 1 82.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The K(+) channel gene families (subdividing into multiple subfamilies) include voltage-gated (K(v): K(v)1-K(v)12 or KCNA-KCND, KCNF-KCNH, KCNQ, KCNS), calcium-activated (K(Ca): K(Ca)1-K(Ca)5 or KCNM-KCNN), inwardly rectifying (K(ir): K(ir)1-K(ir)7 or KCNJ) and background/leak or tandem 2-pore (K(2P): K(2P)1-K(2P)7, K(2P)9-K(2P)10, K(2P)12-K(2P)13, K(2P)15-K(2P)18 or KCNK) K(+) channels.
Localization (voltage-gated) of KCNF-KCNH in pore
1) Confidence 0.05 Published 2007 Journal Recent patents on CNS drug discovery Section Abstract Doc Link 18221232 Disease Relevance 1.27 Pain Relevance 0.42

General Comments

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