INT149883

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Ptgs2) enzyme binding (Ptgs2) protein complex (Ptgs2)
cytoplasm (Ptgs2) signal transducer activity (Agtr2) lipid binding (Ptgs2)
Anatomy Link Frequency
macrophage 2
Agtr2 (Mus musculus)
Ptgs2 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 2 50.00 Quite Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 2 80.60 Quite High
Atherosclerosis 1 78.60 Quite High
INFLAMMATION 1 77.56 Quite High
Pain 1 76.88 Quite High
Stress 1 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Angiotensin II infusion upregulated aortic expression of cyclooxygenase-2 and mPGES-1, increased aortic macrophage recruitment and vascular nitrotyrosine staining (which reflects local oxidative stress), and augmented urinary excretion of the isoprostane 8,12-iso-iPF(2alpha)-VI (which reflects lipid peroxidation in vivo) and the major metabolite of PGE(2) (PGE-M).
Angiotensin II Positive_regulation (upregulated) of Gene_expression (expression) of cyclooxygenase-2 in macrophage
1) Confidence 0.06 Published 2008 Journal Circulation Section Body Doc Link 18285567 Disease Relevance 0.31 Pain Relevance 0

General Comments

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