INT150275

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|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
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fillcolor=green,
 
fillcolor=green,
 
label="Localization",
 
label="Localization",
−
URL=Localization
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=E:Localization"
 
];
 
];
 
node2
 
node2
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fontcolor=white,
 
fontcolor=white,
 
label="MMP8",
 
label="MMP8",
−
URL="MMP8"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:4317"
 
];
 
];
 
subgraph cluster_0 {
 
subgraph cluster_0 {
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{| cellspacing=5 cellpadding=2
 
{| cellspacing=5 cellpadding=2
 
|-
 
|-
−
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[peptidase activity]] ([[MMP8]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:peptidase activity|peptidase activity]] ([[G:4317|MMP8]])
−
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[extracellular space]] ([[MMP8]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:extracellular space|extracellular space]] ([[G:4317|MMP8]])
−
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[extracellular region]] ([[MMP8]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:extracellular region|extracellular region]] ([[G:4317|MMP8]])
 
|-
 
|-
−
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[proteinaceous extracellular matrix]] ([[MMP8]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:proteinaceous extracellular matrix|proteinaceous extracellular matrix]] ([[G:4317|MMP8]])
 
|-
 
|-
 
|}
 
|}
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{| cellpadding=3 cellspacing=0  
 
{| cellpadding=3 cellspacing=0  
 
|-
 
|-
−
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Mention
+
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
|-
 
|-
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:35|brain]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:brain|brain]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
|-
 
|-
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:569|sensory nerves]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:sensory nerves|sensory nerves]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
|-
 
|-
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:86|neutrophils]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:neutrophils|neutrophils]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
|-
 
|-
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
−
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
−
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[metalloproteinase]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:metalloproteinase|metalloproteinase]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 11
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 11
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Inflammation]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Inflammation|Inflammation]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 183
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 183
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Neuropeptide]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Neuropeptide|Neuropeptide]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.68
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.68
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Pain|Pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 95.92
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 95.92
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[substance P]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:substance P|substance P]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 91.20
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 91.20
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[cva]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:cva|cva]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 7
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 7
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 89.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 89.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Inflammatory mediators]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Inflammatory mediators|Inflammatory mediators]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 80.32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 80.32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[rheumatoid arthritis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:rheumatoid arthritis|rheumatoid arthritis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 75.92
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 75.92
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[cINOD]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:cINOD|cINOD]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 70.96
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 70.96
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[ischemia]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:ischemia|ischemia]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 63.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 63.60
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
−
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
−
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[INFLAMMATION]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:INFLAMMATION|INFLAMMATION]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 194
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 194
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Adhesions]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Adhesions|Adhesions]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Dengue Hemorrhagic Fever]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Dengue Hemorrhagic Fever|Dengue Hemorrhagic Fever]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 205
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 205
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Hemorrhage]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Hemorrhage|Hemorrhage]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 75
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 75
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Stroke]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Stroke|Stroke]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 93.92
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 93.92
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Pressure And Volume Under Development]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Pressure And Volume Under Development|Pressure And Volume Under Development]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 90.40
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 90.40
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Pain|Pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 85.08
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 85.08
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Brain Injury]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Brain Injury|Brain Injury]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 83.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 83.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Chorioamnionitis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Chorioamnionitis|Chorioamnionitis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 16
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 16
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 79.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 79.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Atherosclerosis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Atherosclerosis|Atherosclerosis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 76.68
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 76.68
Line 246: Line 246:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
−
|  <span style="color:#000080">'''Localization'''</span> (<span style="color:#000080">secretion</span>) of <span style="color:#800000">'''MMP-8'''</span> in <span style="color:#808000">sensory nerves</span> associated with <span style="color:#FF0000">'''metalloproteinase'''</span> and <span style="color:#FF0000">'''neuropeptide'''</span>
+
|  [[E:Localization|<span style="color:#000080">'''Localization'''</span>]] (<span style="color:#000080">secretion</span>) of [[G:4317|<span style="color:#800000">'''MMP-8'''</span>]] in [[A:sensory nerves|<span style="color:#808000">sensory nerves</span>]] associated with <span style="color:#FF0000">'''metalloproteinase'''</span> and <span style="color:#FF0000">'''neuropeptide'''</span>
 
|-
 
|-
 
|}
 
|}
Line 257: Line 257:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.68
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.68
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Acta Odontol. Scand.|Acta Odontol. Scand.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Acta Odontol. Scand.|Acta Odontol. Scand.]]
Line 277: Line 277:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
−
|  <span style="color:#000080">'''Localization'''</span> (<span style="color:#000080">metalloprotease</span>) of <span style="color:#800000">'''MMP8'''</span> in <span style="color:#808000">neutrophils</span> associated with <span style="color:#FF0000">'''dengue hemorrhagic fever'''</span> and <span style="color:#FF0000">'''adhesions'''</span>
+
|  [[E:Localization|<span style="color:#000080">'''Localization'''</span>]] (<span style="color:#000080">metalloprotease</span>) of [[G:4317|<span style="color:#800000">'''MMP8'''</span>]] in [[A:neutrophils|<span style="color:#808000">neutrophils</span>]] associated with <span style="color:#FF0000">'''dengue hemorrhagic fever'''</span> and <span style="color:#FF0000">'''adhesions'''</span>
 
|-
 
|-
 
|}
 
|}
Line 288: Line 288:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.59
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.59
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
Line 308: Line 308:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
−
|  <span style="color:#000080">'''Localization'''</span> (<span style="color:#000080">release</span>) of <span style="color:#800000">'''MMP-8'''</span> in <span style="color:#808000">brain</span> associated with <span style="color:#FF0000">'''inflammation'''</span> and <span style="color:#FF0000">'''metalloproteinase'''</span>
+
|  [[E:Localization|<span style="color:#000080">'''Localization'''</span>]] (<span style="color:#000080">release</span>) of [[G:4317|<span style="color:#800000">'''MMP-8'''</span>]] in [[A:brain|<span style="color:#808000">brain</span>]] associated with <span style="color:#FF0000">'''inflammation'''</span> and <span style="color:#FF0000">'''metalloproteinase'''</span>
 
|-
 
|-
 
|}
 
|}
Line 319: Line 319:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.47
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.47
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Ann. N. Y. Acad. Sci.|Ann. N. Y. Acad. Sci.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Ann. N. Y. Acad. Sci.|Ann. N. Y. Acad. Sci.]]
Line 340: Line 340:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
−
|  <span style="color:#000080">'''Localization'''</span> (<span style="color:#000080">metalloprotease</span>) of <span style="color:#800000">'''MMP-8'''</span>
+
|  [[E:Localization|<span style="color:#000080">'''Localization'''</span>]] (<span style="color:#000080">metalloprotease</span>) of [[G:4317|<span style="color:#800000">'''MMP-8'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 351: Line 351:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.16
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.16
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
Line 371: Line 371:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
−
|  <span style="color:#000080">'''Localization'''</span> (<span style="color:#000080">performed</span>) of <span style="color:#800000">'''MMP-8'''</span>
+
|  [[E:Localization|<span style="color:#000080">'''Localization'''</span>]] (<span style="color:#000080">performed</span>) of [[G:4317|<span style="color:#800000">'''MMP-8'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 382: Line 382:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.14
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.14
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]

Latest revision as of 12:45, 20 September 2012

Context Info
Confidence 0.68
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.57
Pain Relevance 1.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP8) extracellular space (MMP8) extracellular region (MMP8)
proteinaceous extracellular matrix (MMP8)
Anatomy Link Frequency
brain 1
sensory nerves 1
neutrophils 1
MMP8 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 11 100.00 Very High Very High Very High
Inflammation 183 99.14 Very High Very High Very High
Neuropeptide 2 97.68 Very High Very High Very High
Pain 3 95.92 Very High Very High Very High
substance P 2 91.20 High High
cva 7 89.84 High High
Inflammatory mediators 4 80.32 Quite High
rheumatoid arthritis 1 75.92 Quite High
cINOD 2 70.96 Quite High
ischemia 1 63.60 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 194 99.14 Very High Very High Very High
Adhesions 1 98.72 Very High Very High Very High
Dengue Hemorrhagic Fever 205 98.14 Very High Very High Very High
Hemorrhage 75 97.72 Very High Very High Very High
Stroke 6 93.92 High High
Pressure And Volume Under Development 1 90.40 High High
Pain 3 85.08 High High
Brain Injury 1 83.60 Quite High
Chorioamnionitis 16 79.60 Quite High
Atherosclerosis 2 76.68 Quite High

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The pro-inflammatory neuropeptides released by sensory nerves coordinate the activities of the immuno-effector cells and may influence the secretion of MMP-8.
Localization (secretion) of MMP-8 in sensory nerves associated with metalloproteinase and neuropeptide
1) Confidence 0.68 Published 2008 Journal Acta Odontol. Scand. Section Abstract Doc Link 18320414 Disease Relevance 0.34 Pain Relevance 0.75
A putative neutrophil origin of this gene expression pattern is however supported by the over-expression in DSS patients blood cells of transcripts encoding other neutrophil-related molecules such as the MMP8 matrix metalloprotease, CEACAM-6, CEACAM-8 and CD99L2 adhesion molecules (Tables 4 and S2) involved in the recruitment of neutrophils to vascular endothelia.
Localization (metalloprotease) of MMP8 in neutrophils associated with dengue hemorrhagic fever and adhesions
2) Confidence 0.59 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2907396 Disease Relevance 1.16 Pain Relevance 0.22
Although the exact cellular source of MMPs remains unknown, brain endothelium, astrocytes, neurons, and inflammatory-activated cells, such as neutrophils, may release MMP-2, MMP-3, MMP-8, MMP-9, MMP-10, and/or MMP-13.
Localization (release) of MMP-8 in brain associated with inflammation and metalloproteinase
3) Confidence 0.47 Published 2010 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 20955435 Disease Relevance 1.07 Pain Relevance 0.52
Immunoassays for interleukin-6 (IL-6) and matrix metalloprotease-8 (MMP-8)
Localization (metalloprotease) of MMP-8
4) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2315798 Disease Relevance 0.51 Pain Relevance 0.13
ELISA for human IL-6 (Pierce-Endogen, Rockford, IL) and MMP-8 (R&D Systems, Minneapolis, MN) were performed in duplicate by investigators unaware of clinical outcomes.
Localization (performed) of MMP-8
5) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2315798 Disease Relevance 0.49 Pain Relevance 0.12

[edit] General Comments

This test has worked.

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