INT150838

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.98
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Adm) extracellular region (Adm) response to stress (Adm)
cytoplasm (Adm)
Anatomy Link Frequency
dorsal root ganglion 2
Adm (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 2 97.84 Very High Very High Very High
IPN 2 96.92 Very High Very High Very High
dorsal root ganglion 5 95.84 Very High Very High Very High
Calcitonin gene-related peptide 4 89.00 High High
Pyramidal cell 3 79.84 Quite High
antagonist 2 76.08 Quite High
cerebral cortex 6 75.00 Quite High
Inflammation 5 75.00 Quite High
headache 3 65.88 Quite High
Hyperalgesia 1 65.52 Quite High
Disease Link Frequency Relevance Heat
Inflammatory Pain 2 96.92 Very High Very High Very High
Ganglion Cysts 5 95.36 Very High Very High Very High
Hypoxia 9 75.00 Quite High
INFLAMMATION 3 75.00 Quite High
Vomiting 3 66.32 Quite High
Headache 3 65.88 Quite High
Hyperalgesia 2 65.52 Quite High
Dizziness 3 64.64 Quite High
Sleep Disorders 3 64.20 Quite High
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Real-time PCR quantification of AM mRNA and Western blotting confirmed the up-regulation of AM expression following hypobaria.
Positive_regulation (up) of Gene_expression (expression) of AM
1) Confidence 0.06 Published 2008 Journal Brain Pathol. Section Abstract Doc Link 18371176 Disease Relevance 0.47 Pain Relevance 0.18
In addition, hypobaria modulates alternative splicing of the AM gene resulting in a higher production of AM.
Positive_regulation (higher) of Gene_expression (production) of AM
2) Confidence 0.06 Published 2008 Journal Brain Pathol. Section Abstract Doc Link 18371176 Disease Relevance 0.44 Pain Relevance 0.17
In addition, hypobaria modulates alternative splicing of the AM gene resulting in a higher production of AM.
Positive_regulation (resulting) of Gene_expression (production) of AM
3) Confidence 0.06 Published 2008 Journal Brain Pathol. Section Abstract Doc Link 18371176 Disease Relevance 0.44 Pain Relevance 0.17
Injection of CFA, but not of saline, in the unilateral hindpaw produced an increase in the expression of AM-like immunoreactivity (AM-IR) in laminae I-II of the spinal cord as well as in small- and medium-sized dorsal root ganglion (DRG) neurons at 48 h.
Spec (like) Positive_regulation (increase) of Gene_expression (expression) of AM in dorsal root ganglion associated with ganglion cysts, dorsal root ganglion and spinal cord
4) Confidence 0.01 Published 2009 Journal Pain Section Abstract Doc Link 19683388 Disease Relevance 0.64 Pain Relevance 0.59

General Comments

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