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Context Info
Confidence 0.15
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.19
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Fgfr1) nucleus (Fgfr1) kinase activity (Fgfr1)
cytoplasm (Fgfr1)
Anatomy Link Frequency
connective tissue 2
fibroblast 2
PANC-1 2
Fgfr1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 53 99.48 Very High Very High Very High
Inflammation 46 75.00 Quite High
cINOD 3 75.00 Quite High
psoriasis 44 23.92 Low Low
chemokine 17 21.56 Low Low
rheumatoid arthritis 88 7.24 Low Low
Multiple sclerosis 48 5.00 Very Low Very Low Very Low
Arthritis 26 5.00 Very Low Very Low Very Low
Adalimumab 9 5.00 Very Low Very Low Very Low
Etanercept 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 57 97.60 Very High Very High Very High
Hypersensitivity 1 96.96 Very High Very High Very High
Cancer 51 96.52 Very High Very High Very High
Death 15 94.44 High High
Systemic Sclerosis 34 91.72 High High
Shock 1 87.44 High High
Targeted Disruption 7 83.12 Quite High
Ulcers 1 81.92 Quite High
Apoptosis 15 76.00 Quite High
INFLAMMATION 47 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, transfection of a truncated FGFR-1 into PANC-1 cells induces the blockade of FGF receptor-dependent pathways and reduces tumour growth in nude mice [28].
Positive_regulation (transfection) of Gene_expression (transfection) of FGFR-1 in PANC-1 associated with cancer
1) Confidence 0.15 Published 2003 Journal Mol Cancer Section Body Doc Link PMC149419 Disease Relevance 1.37 Pain Relevance 0
Cytokine or cytokine receptor patterns showed high expression of CCR1, FGFR1, connective tissue growth factor (CTGF), FGF7, and SCYA19 in biopsies from SSC patients.
Positive_regulation (high) of Gene_expression (expression) of FGFR1 in connective tissue associated with hypersensitivity and cytokine
2) Confidence 0.12 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 1.11 Pain Relevance 0.10
Lansoprazole favors mucosal cell renewal simultaneously by stimulating gene expression of prosurvival proliferating cell nuclear antigen, survivin, epidermal growth factor, and basic fibroblast growth factor.
Positive_regulation (stimulating) of Gene_expression (expression) of basic fibroblast growth factor in fibroblast
3) Confidence 0.01 Published 2008 Journal J. Biol. Chem. Section Abstract Doc Link 18375387 Disease Relevance 0.70 Pain Relevance 0.22

General Comments

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