INT151

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Context Info
Confidence 0.62
First Reported 1977
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.42
Pain Relevance 1.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Por) oxidoreductase activity (Por) endoplasmic reticulum (Por)
enzyme binding (Por)
Por (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 10 99.98 Very High Very High Very High
Potency 1 92.24 High High
halothane 8 86.68 High High
Morphine 1 78.20 Quite High
c fibre 2 77.44 Quite High
nociceptor 6 75.00 Quite High
Pain 2 58.48 Quite High
anesthesia 1 25.00 Low Low
ischemia 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 16 66.88 Quite High
Nociception 2 66.60 Quite High
Arrhythmias 2 Under Development 44 61.20 Quite High
Pain 2 58.48 Quite High
Hepatotoxicity 1 25.00 Low Low
Emergencies 4 5.00 Very Low Very Low Very Low
Myocardial Infarction 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Heart Rate Under Development 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further, the N-demethylation was stoichiometric with the stimulation of both NADPH-cytochrome P-450 reductase and NADPH oxidase, whereas the sum of the N-demethylation and O-de-ethylation was significantly greater, suggesting that the O-de-ethylase activity does not involve stimulation of either of these two activities.
Positive_regulation (stimulation) of NADPH-cytochrome P-450 reductase
1) Confidence 0.62 Published 1977 Journal Drug Metab. Dispos. Section Abstract Doc Link 13981 Disease Relevance 0 Pain Relevance 0.08
Daily administration of PB, TP, TA, or PT induced cytochrome P-450, NADPH-cytochrome P-450 reductase and/or cytochrome b5.
Positive_regulation (induced) of NADPH-cytochrome P-450
2) Confidence 0.45 Published 1990 Journal Hiroshima J. Med. Sci. Section Abstract Doc Link 2086563 Disease Relevance 0 Pain Relevance 0.23
Recognizing that even those patients with a response interval less than 5 min did no worse with 'CPR first' (Fig. 2), Wik and colleagues concluded that 3 min of CPR before defibrillation attempts is always indicated unless the patient collapsed in front of EMS.
Positive_regulation (indicated) of CPR
3) Confidence 0.33 Published 2004 Journal Crit Care Section Body Doc Link PMC420055 Disease Relevance 0.18 Pain Relevance 0
After repetitive heat stimuli, ATP-induced CPR excitation was increased (10(-5) to 10(-3) M), but none of the purinergic agonists induced CPR excitation in a magnitude comparable to that by ATP.
Positive_regulation (induced) of CPR associated with agonist
4) Confidence 0.31 Published 2005 Journal Neurosci. Res. Section Abstract Doc Link 15740803 Disease Relevance 0.12 Pain Relevance 0.49
After repetitive heat stimuli, ATP-induced CPR excitation was increased (10(-5) to 10(-3) M), but none of the purinergic agonists induced CPR excitation in a magnitude comparable to that by ATP.
Positive_regulation (increased) of CPR associated with agonist
5) Confidence 0.31 Published 2005 Journal Neurosci. Res. Section Abstract Doc Link 15740803 Disease Relevance 0.13 Pain Relevance 0.51

General Comments

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