INT15122

From wiki-pain
Revision as of 10:19, 22 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.24
First Reported 1984
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 5.20
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cacna2d2)
Cacna2d2 (Mus musculus)
Pain Link Frequency Relevance Heat
lidocaine 2 99.42 Very High Very High Very High
potassium channel 3 99.22 Very High Very High Very High
Action potential 7 97.76 Very High Very High Very High
Angina 2 86.88 High High
anesthesia 3 82.08 Quite High
Calcium channel 1 61.44 Quite High
Disease Link Frequency Relevance Heat
Arrhythmia Under Development 45 100.00 Very High Very High Very High
Cv Unclassified Under Development 6 100.00 Very High Very High Very High
Premature Ventricular Beats 1 100.00 Very High Very High Very High
Arrhythmias 2 Under Development 1 97.12 Very High Very High Very High
Overdose 2 95.00 High High
Heart Rate Under Development 6 91.32 High High
Death 1 90.12 High High
Myocardial Infarction 2 89.20 High High
Cv General 3 Under Development 2 86.88 High High
Hypertension 2 84.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A bolus of 1.0 to 2.0 g MgSO4 25% abolished the TdP in all 3 patients; but in the third patient, because of recurrent TdP, a second bolus of 1.0 g and a continuous 24-hour infusion of 1.0 mg/min were administered, preventing TdP.
Negative_regulation (abolished) of TdP associated with arrhythmia under development
1) Confidence 0.24 Published 1984 Journal Am. J. Cardiol. Section Abstract Doc Link 6695782 Disease Relevance 1.04 Pain Relevance 0.07
Nicorandil, a potassium channel opener, shortened the QT interval and abolished TdP.
Negative_regulation (abolished) of TdP associated with potassium channel
2) Confidence 0.24 Published 1999 Journal Pacing Clin Electrophysiol Section Abstract Doc Link 10234727 Disease Relevance 0.25 Pain Relevance 0.23
A bolus of 1.0 to 2.0 g MgSO4 25% abolished the TdP in all 3 patients; but in the third patient, because of recurrent TdP, a second bolus of 1.0 g and a continuous 24-hour infusion of 1.0 mg/min were administered, preventing TdP.
Negative_regulation (preventing) of TdP associated with arrhythmia under development
3) Confidence 0.24 Published 1984 Journal Am. J. Cardiol. Section Abstract Doc Link 6695782 Disease Relevance 1.05 Pain Relevance 0.09
Dron, i.v., suppressed the EADs, EBs, and TdP by a reduction and homogenization of repolarization (LV(APD), 505 +/- 110 to 455 +/- 80 ms, and deltaAPD, 110 +/- 55 to 65 +/- 40 ms).
Negative_regulation (suppressed) of TdP associated with cv unclassified under development and arrhythmia under development
4) Confidence 0.17 Published 1999 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 10028928 Disease Relevance 0.80 Pain Relevance 0.03
In contrast to oral treatment, Dron i.v. shortens ventricular repolarization parameters, resulting in suppression of EAD-dependent acquired TdP.
Negative_regulation (suppression) of TdP associated with arrhythmia under development
5) Confidence 0.12 Published 1999 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 10028928 Disease Relevance 0.65 Pain Relevance 0
Intravenous administration of lidocaine or right ventricular pacing suppressed the ventricular premature complexes and TdP in association with the suppression of the EADs on the MAPs.
Negative_regulation (suppressed) of TdP associated with action potential, arrhythmia under development, lidocaine and premature ventricular beats
6) Confidence 0.01 Published 1991 Journal Pacing Clin Electrophysiol Section Abstract Doc Link 1715547 Disease Relevance 0.91 Pain Relevance 0.31
These results suggest that IKr channel inhibition by amiodarone with its additional ion channel blocking action may contribute to the prevention of TdP.
Negative_regulation (prevention) of TdP associated with arrhythmia under development
7) Confidence 0.01 Published 2002 Journal Circ. J. Section Abstract Doc Link 12197602 Disease Relevance 0.49 Pain Relevance 0.11

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox