INT151780

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Calca, Camkk2) extracellular space (Calca) extracellular region (Calca)
nucleus (Calca) intracellular (Calca) kinase activity (Camkk2)
Anatomy Link Frequency
neuronal 1
Calca (Mus musculus)
Camkk2 (Mus musculus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 9 100.00 Very High Very High Very High
Trigeminal ganglion neurons 1 99.48 Very High Very High Very High
medulla 1 84.76 Quite High
Migraine 2 79.76 Quite High
Pain 3 75.64 Quite High
nociceptor 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 99.16 Very High Very High Very High
Headache 2 79.76 Quite High
Nociception 1 78.32 Quite High
Pain 3 75.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CGRP activated Ca(2+)-calmodulin-dependent kinase II, which became localized to the perimembrane region and neuronal processes, a phenomenon already apparent after 30 min and accompanied by a parallel increase in cAMP-response element-binding protein (CREB) phosphorylation and nuclear translocation.
CGRP Positive_regulation (activated) of kinase II in neuronal associated with calcitonin gene-related peptide
1) Confidence 0.01 Published 2008 Journal J. Biol. Chem. Section Abstract Doc Link 18460469 Disease Relevance 0.48 Pain Relevance 0.61

General Comments

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