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Context Info
Confidence 0.40
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.97
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TH1L) nucleus (TH1L)
Anatomy Link Frequency
Treg 2
TH1L (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 23 98.40 Very High Very High Very High
agonist 2 53.48 Quite High
peptic ulcer disease 1 50.00 Quite Low
Inflammation 7 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
transdermal 2 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 51 95.64 Very High Very High Very High
Anaerobic Bacterial Infections 3 82.56 Quite High
Skin Cancer 40 69.12 Quite High
Ulcers 4 50.00 Quite Low
Disease 3 50.00 Quite Low
Eosinophilia 4 26.72 Quite Low
Mouth Cancer 6 22.64 Low Low
Malignant Neoplastic Disease 6 12.48 Low Low
Immunization 7 5.00 Very Low Very Low Very Low
INFLAMMATION 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This finding likely has relevance for others using IFA adjuvants, as it reflects an unbalanced early Th2 dominance with the potential to compromise induction of Th1 and Tc1 responses.
Positive_regulation (induction) of Regulation (responses) of Th1
1) Confidence 0.40 Published 2010 Journal J Transl Med Section Body Doc Link PMC2936306 Disease Relevance 0.23 Pain Relevance 0.03
People with peptic ulcer disease had a 2.4-fold reduced CD4(+)CD25(hi)IL10(+) Treg response (p = 0.05) but increased Th1 and Th2 responses (Th1: 3.2-fold, p = 0.038; Th2: 6.1-fold, p = 0.029) compared to those without ulcers.
Positive_regulation (increased) of Regulation (responses) of Th1 in Treg
2) Confidence 0.10 Published 2008 Journal Gut Section Body Doc Link 18467372 Disease Relevance 0 Pain Relevance 0
Our study also showed that "Shenyang" induced an up-regulation of Th1-type and a down-regulation of Th2-type cytokines, which is a possible mechanism for improving cellular immune function.
Positive_regulation (induced) of Regulation (regulation) of Th1 associated with cytokine
3) Confidence 0.08 Published 2007 Journal BMC Cancer Section Body Doc Link PMC1821034 Disease Relevance 0.74 Pain Relevance 0.21

General Comments

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