INT152504

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnf) extracellular space (Tnf) extracellular region (Tnf)
plasma membrane (Tnf) intracellular (Tnf) extracellular matrix organization (Tnf)
CR1 (Homo sapiens)
Tnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 1 99.70 Very High Very High Very High
c fibre 2 97.34 Very High Very High Very High
Adelta 4 97.18 Very High Very High Very High
dorsal root ganglion 1 93.12 High High
substantia gelatinosa 4 92.60 High High
Spinal cord 2 75.00 Quite High
Dorsal horn 1 75.00 Quite High
allodynia 1 71.44 Quite High
Thermal hyperalgesia 1 68.56 Quite High
withdrawal 1 67.20 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 92.16 High High
Necrosis 2 75.00 Quite High
Cancer 2 75.00 Quite High
Neuropathic Pain 2 71.44 Quite High
Hyperalgesia 1 68.56 Quite High
INFLAMMATION 1 52.48 Quite High
Pain 1 5.00 Very Low Very Low Very Low
Hypersensitivity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of TNF-alpha on Adelta/C fiber-evoked monosynaptic and polysynaptic or spontaneous EPSCs were significantly blocked by 5 microM TNF-alpha antagonist that inhibits TNF-alpha binding to its type 1 receptor (TNFR1).
type 1 receptor Binding (binding) of TNF-alpha associated with c fibre, antagonist and adelta
1) Confidence 0.00 Published 2008 Journal J. Neurosci. Res. Section Abstract Doc Link 18543334 Disease Relevance 0.49 Pain Relevance 1.04

General Comments

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