INT152666
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
The compound (ICG-001; Figure 4) described by Kahn et al. showed specific affinity and inhibition of CBP, and proved effective in preventing CBP-mediated transcriptional activation and ? | |||||||||||||||
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-catenin/Tcf4 transcriptional pathway by inhibiting cyclic AMP response element-binding protein (CBP) (Figure 4) [70, 171]. | |||||||||||||||
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RESULTS: RRME inhibited both p300 and CBP (60-70% at 100 microg/ml) activity. | |||||||||||||||
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General Comments
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