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Context Info
Confidence 0.42
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (P2rx7) mitochondrion organization (P2rx7) protein complex (P2rx7)
transmembrane transport (P2rx7) cytoplasm (P2rx7) cell death (P2rx7)
P2rx7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 7 98.68 Very High Very High Very High
agonist 2 78.24 Quite High
Pain 1 66.48 Quite High
Inflammation 2 66.12 Quite High
cytokine 1 56.36 Quite High
Disease Link Frequency Relevance Heat
Pain 1 66.48 Quite High
INFLAMMATION 2 66.12 Quite High
Targeted Disruption 1 61.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The pharmacological profile for P2X antagonists to inhibit [3H]A-804598 binding correlated with their ability to block functional activation of P2X7 receptors (r=0.95, P<0.05).
Negative_regulation (block) of Positive_regulation (activation) of P2X7 associated with antagonist
1) Confidence 0.42 Published 2009 Journal Neuropharmacology Section Abstract Doc Link 18602931 Disease Relevance 0.25 Pain Relevance 0.50

General Comments

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