INT153219

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Context Info
Confidence 0.42
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.80
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CXCL10) extracellular space (CXCL10) extracellular region (CXCL10)
cell-cell signaling (CXCL10)
Anatomy Link Frequency
coronary artery 2
CXCL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 16 99.80 Very High Very High Very High
Inflammation 6 99.40 Very High Very High Very High
chemokine 12 93.00 High High
Inflammatory response 2 52.44 Quite High
Angina 1 35.76 Quite Low
Neurobehavioral 7 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
glial activation 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 8 99.40 Very High Very High Very High
Hepatitis C Virus Infection 189 98.44 Very High Very High Very High
Atherosclerosis 2 96.96 Very High Very High Very High
Coronary Artery Disease 8 93.92 High High
Injury 11 58.96 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 73 50.00 Quite Low
Infection 34 44.60 Quite Low
Cv General 3 Under Development 1 35.76 Quite Low
Viremia 2 14.12 Low Low
Drug Induced Neurotoxicity 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
expressed elevated levels of CXCL10 and CXCL8 transcripts (Figure 3A and 3C, p<0.05).
Positive_regulation (elevated) of Transcription (levels) of CXCL10
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943470 Disease Relevance 1.11 Pain Relevance 0.31
We evaluated mRNA expression and protein production of CCL2, CXCL8, CXCL9, CXCL10, IFN-gamma and IL-10 in vitro as well as the expression of the CCR2 and CXCR3 receptors in peripheral blood mononuclear cells (PBMCs) of patients with coronary artery disease (CAD) and healthy controls in the presence or absence of oxidized LDL (oxLDL).
Positive_regulation (evaluated) of Transcription (expression) of CXCL10 in coronary artery associated with coronary artery disease
2) Confidence 0.11 Published 2009 Journal Int. J. Cardiol. Section Abstract Doc Link 18617279 Disease Relevance 0.69 Pain Relevance 0.26

General Comments

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