INT153853

From wiki-pain
Revision as of 06:16, 21 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 7
Total Number 10
Disease Relevance 8.43
Pain Relevance 1.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

RNA binding (Fus) nucleus (Fus) intracellular (Fus)
DNA binding (Fus) cytoplasm (Fus)
Anatomy Link Frequency
brain 2
hippocampus 1
Fus (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 388 100.00 Very High Very High Very High
Hippocampus 30 97.60 Very High Very High Very High
Inflammation 4 95.92 Very High Very High Very High
fibrosis 4 94.80 High High
Thalamus 25 83.12 Quite High
Tendonitis 2 69.36 Quite High
anesthesia 9 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
ketamine 5 5.00 Very Low Very Low Very Low
cva 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 130 100.00 Very High Very High Very High
Neurodegenerative Disease 30 100.00 Very High Very High Very High
Fever 16 100.00 Very High Very High Very High
Cancer 376 99.80 Very High Very High Very High
Breast Cancer 268 99.16 Very High Very High Very High
Necrosis 72 98.12 Very High Very High Very High
Alzheimer's Dementia 60 97.24 Very High Very High Very High
Malignant Neoplastic Disease 28 97.00 Very High Very High Very High
INFLAMMATION 4 95.92 Very High Very High Very High
Fibrosis 4 94.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is unclear from these experiments if a single FUS-MB enhanced anti-A?
Positive_regulation (single) of FUS-MB
1) Confidence 0.42 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2364662 Disease Relevance 0.54 Pain Relevance 0.20
Others have suggested that the targeting capabilities of FUS-MB could be applied for drug delivery to small anatomical targets, such as the hippocampus [24].
Positive_regulation (applied) of FUS-MB in hippocampus associated with hippocampus
2) Confidence 0.42 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2364662 Disease Relevance 0.09 Pain Relevance 0.21
More recently, Furusawa et al. published improved results of MRI-guided FUS for tumour ablation in a group of 30 breast cancer patients [45].
Positive_regulation (results) of FUS associated with cancer, breast cancer and imagery
3) Confidence 0.38 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 1.66 Pain Relevance 0.32
When FUS ablation is performed for curative treatment of breast cancer, preferentially, patients with large tumours (>5 cm) should not be selected for FUS ablation as increased tumour size significantly increases the treatment time and the probability of complete tumour necrosis decreases substantially [42].
Neg (not) Positive_regulation (selected) of FUS associated with necrosis, cancer and breast cancer
4) Confidence 0.38 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 1.32 Pain Relevance 0.16
This first experience of MRI-guided FUS for treatment of benign breast tumours was reported by Hynynen et al. in 2001 [39].
Positive_regulation (experience) of FUS associated with breast cancer and imagery
5) Confidence 0.38 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 0.89 Pain Relevance 0.17
We believe that FUS-MB may be used for imaging and drug delivery in transgenic models of neurodegenerative diseases besides Alzheimer's, and could be used for delivering functional imaging probes to the brain for basic research.
Positive_regulation (used) of FUS-MB in brain associated with targeted disruption, neurodegenerative disease and imagery
6) Confidence 0.36 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2364662 Disease Relevance 0.65 Pain Relevance 0.22
We believe that FUS-MB may be used for imaging and drug delivery in transgenic models of neurodegenerative diseases besides Alzheimer's, and could be used for delivering functional imaging probes to the brain for basic research.
Positive_regulation (used) of FUS-MB in brain associated with targeted disruption, neurodegenerative disease and imagery
7) Confidence 0.36 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2364662 Disease Relevance 0.64 Pain Relevance 0.21
Future research will focus on FUS hyperthermia-induced activation of a therapeutic (trans) gene, such as tumour necrosis factor ?
Positive_regulation (activation) of FUS associated with necrosis, cancer and fever
8) Confidence 0.35 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 1.35 Pain Relevance 0
Additionally, we wanted to use a simple benchtop sonication system to allow high throughput FUS-MB for drug studies.
Positive_regulation (allow) of FUS-MB
9) Confidence 0.34 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2364662 Disease Relevance 1.08 Pain Relevance 0.04
CSA-l, FPS and TLS were better in all patients, with an appreciable filling of lesions indicated by a decreasing of CSA-l and increasing of TLS.
Positive_regulation (increasing) of TLS
10) Confidence 0.04 Published 2008 Journal Vet. Res. Commun. Section Abstract Doc Link 18686004 Disease Relevance 0.22 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox