INT153990

Context Info Confidence 0.49 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.40 Pain Relevance 0.42

cytosol (AKAP5) signal transduction (AKAP5) small molecule metabolic process (AKAP5) protein targeting (AKAP5) plasma membrane (AKAP5)

AKAP5 (Homo sapiens)

Pain Link Frequency Relevance Heat bradykinin 1 95.36 Hyperalgesia 2 88.08 Inflammatory mediators 2 83.92 Pain 1 80.60 Inflammation 1 76.76

Disease Link Frequency Relevance Heat INFLAMMATION 3 83.52 Hyperalgesia 2 82.72 Injury 1 76.12

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We identify a critical region in the TRPV1 C-terminal which mediates binding of AKAP79/150.

Positive_regulation (mediates) of AKAP79 Binding (binding) of

1) Confidence 0.49 Published 2008 Journal Neuron Section Abstract Doc Link 18701070 Disease Relevance 0.40 Pain Relevance 0.42

General Comments

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