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Context Info
Confidence 0.30
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ifng, Il10) extracellular region (Ifng, Il10) intracellular (Il10)
Anatomy Link Frequency
PGE2 1
Ifng (Rattus norvegicus)
Il10 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 3 98.20 Very High Very High Very High
aspirin 4 97.92 Very High Very High Very High
cytokine 5 96.50 Very High Very High Very High
Inflammation 2 90.48 High High
Disease Link Frequency Relevance Heat
Necrosis 1 99.10 Very High Very High Very High
Cancer 1 98.92 Very High Very High Very High
Peptic Ulcer 2 91.88 High High
INFLAMMATION 2 90.48 High High
Toxicity 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Analysis of serum cytokine profile using enzymelinked immunosorbent assay (ELISA) showed a drastic increase in interleukin (IL)-1beta, IL-6, tumour necrosis factor-alpha (TNF)-alpha, interferon-gamma (IFN-gamma) and decrease in IL-10, Il-4 and prostaglandin E2 (PGE2) levels in NSAID (aspirin) treated rats.
IFN-gamma Negative_regulation (decrease) of IL-10 in PGE2 associated with aspirin, necrosis, cancer, cinod and cytokine
1) Confidence 0.30 Published 2008 Journal Int. Immunopharmacol. Section Abstract Doc Link 18773975 Disease Relevance 0.61 Pain Relevance 0.60

General Comments

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