INT154607

Context Info Confidence 0.37 First Reported 2008 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.68 Pain Relevance 0.75

endoplasmic reticulum (DDOST) translation (DDOST) protein complex (DDOST)

DDOST (Homo sapiens)

Pain Link Frequency Relevance Heat drug abuse 10 99.84 addiction 32 96.64 Buprenorphine 70 95.08 agonist 4 94.52 methadone 40 93.60 mu opioid receptor 2 92.88 Opioid 17 90.64 narcan 24 5.00 MU agonist 8 5.00 Pain 4 5.00

Disease Link Frequency Relevance Heat Substance Abuse 11 99.84 Opiate Addiction 29 96.64 Acquired Immune Deficiency Syndrome Or Hiv Infection 4 50.84 Cognitive Disorder 22 5.00 Pain 4 5.00 Attention Deficit Hyperactivity Disorder 2 5.00 Intellectual Impairment 2 5.00 Substance Withdrawal Syndrome 1 5.00 Poisoning 1 5.00 Mental Disorders 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

CONCLUSIONS: Both access to and effectiveness of OST contribute to sustaining adherence to HAART in HIV-infected IDUs.

Negative_regulation (effectiveness) of OST

1) Confidence 0.37 Published 2008 Journal Addiction Section Body Doc Link 18778390 Disease Relevance 0.10 Pain Relevance 0

Follow-up studies of OST patients have shown consistently high retention in OST, fewer crimes, reduction in substance abuse, and improved health [3,4].

Negative_regulation (reduction) of OST associated with drug abuse

2) Confidence 0.35 Published 2009 Journal Subst Abuse Treat Prev Policy Section Body Doc Link PMC2676265 Disease Relevance 0.58 Pain Relevance 0.75

General Comments

This test has worked.