INT155152

Context Info Confidence 0.32 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.05 Pain Relevance 0.09

Anatomy Link Frequency crest 1 Lch (Mus musculus)

Pain Link Frequency Relevance Heat Pain 1 90.00 methotrexate 1 25.00

Disease Link Frequency Relevance Heat Langerhans-cell Histiocytosis 6 100.00 Papular Skin Disease 1 96.96 Juvenile Xanthogranuloma 7 93.92 Diabetes Insipidus 1 91.88

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

An iliac crest bone biopsy showed an eosinophil-rich infiltrate admixed with histiocytoid cells with reniform nuclei, which expressed S100 and CD1a, consistent with a diagnosis of LCH.

Negative_regulation (diagnosis) of LCH in crest associated with langerhans-cell histiocytosis

1) Confidence 0.32 Published 2008 Journal J. Cutan. Pathol. Section Abstract Doc Link 18840155 Disease Relevance 1.05 Pain Relevance 0.09

General Comments

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