INT155865

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Context Info
Confidence 0.46
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.60
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (COL1A2) extracellular region (COL1A2) protein binding, bridging (COL1A2)
Anatomy Link Frequency
articular 2
tendon fibroblasts 2
COL1A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 40 91.04 High High
Inflammation 18 90.52 High High
Osteoarthritis 141 87.68 High High
diclofenac 13 5.00 Very Low Very Low Very Low
metalloproteinase 12 5.00 Very Low Very Low Very Low
cINOD 9 5.00 Very Low Very Low Very Low
Analgesic 3 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Onset of action 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 39 91.04 High High
INFLAMMATION 20 90.52 High High
Osteoarthritis 143 87.68 High High
Scurvy 1 49.16 Quite Low
Disease 12 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Chronic Disease 3 5.00 Very Low Very Low Very Low
Osteophyte 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Low-level laser irradiation promotes cell proliferation and mRNA expression of type I collagen and decorin in porcine Achilles tendon fibroblasts in vitro.
Positive_regulation (promotes) of Transcription (expression) of type I collagen in tendon fibroblasts
1) Confidence 0.46 Published 2009 Journal J. Orthop. Res. Section Title Doc Link 18991342 Disease Relevance 0.18 Pain Relevance 0.14
In vitro, ascorbate and ascorbic acid increased protein and proteoglycan synthesis by articular chondrocytes [64,66,67] and increased the mRNA levels of type I and II collagen [64,68] and aggrecan and ?
Positive_regulation (increased) of Transcription (levels) of type I and II collagen in articular
2) Confidence 0.04 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779427 Disease Relevance 0.42 Pain Relevance 0.21

General Comments

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