INT155918

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Context Info
Confidence 0.34
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (NFKB1, TNF) nucleoplasm (NFKB1) mitochondrion (NFKB1)
intracellular (TNF) extracellular matrix organization (TNF) cytoplasm (NFKB1)
Anatomy Link Frequency
MNCs 2
NFKB1 (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 4 50.00 Quite Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 4 50.00 Quite Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpressed PARP-1 promotes PARP-1/NF-kappaB/DNA complex formation, thereby enhancing the expression of TNF-alpha and IL-6 in circulating MNCs of UA patients.


NF-kappaB Positive_regulation (enhancing) of Gene_expression (expression) of TNF-alpha in MNCs
1) Confidence 0.34 Published 2008 Journal Arch. Med. Res. Section Body Doc Link 18996291 Disease Relevance 0 Pain Relevance 0

General Comments

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